tert-Butyl 6-bromobenzo[d]isothiazole-3-carboxylate

Base Information

• Chemical Name: tert-Butyl 6-bromobenzo[d]isothiazole-3-carboxylate
• CAS No.: 932702-07-3
• Molecular Formula: C₁₂H₁₂BrNO₂S
• Molecular Weight: 314.203
• Hs Code.: 2934999090
• Mol file: 932702-07-3.mol

Synonyms:6-Bromo-1,2-benzisothiazole-3-carboxylic acid 1,1-dimethylethyl ester;tert-Butyl 6-bromobenzo[d]isothiazole-3-carboxylate;

Chemical Property of tert-Butyl 6-bromobenzo[d]isothiazole-3-carboxylate

Chemical Property:

• Refractive Index: 1.621
• Boiling Point: 340.6 °C at 760 mmHg
• Flash Point: 159.8 °C
• PSA: 67.43000
• Density: 1.496 g/cm³
• LogP: 4.01410

Purity/Quality:

98% ^*data from raw suppliers

tert-Butyl6-bromobenzo[d]isothiazole-3-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tert-Butyl 6-bromobenzo[d]isothiazole-3-carboxylate

There total 2 articles about tert-Butyl 6-bromobenzo[d]isothiazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

6-bromo-benzo[d]isothiazole-3-carboxylic acid (677304-75-5) + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl 6-bromo-benzo[d]isothiazole-3-carboxylate (932702-07-3)

Guidance literature:

With dmap; In tetrahydrofuran; tert-butyl alcohol; at 65 ℃; for 16h;

Reference yield: 99.0%

6-bromo-benzo[d]isothiazole-3-carboxylic acid (677304-75-5) + di-tert-butyl dicarbonate (24424-99-5) + tert-butyl alcohol (75-65-0) → tert-butyl 6-bromo-benzo[d]isothiazole-3-carboxylate (932702-07-3)

Guidance literature:

With dmap; In tetrahydrofuran; at 65 ℃; for 16h;

upstream raw materials:

6-bromo-benzo[d]isothiazole-3-carboxylic acid

di-tert-butyl dicarbonate

tert-butyl alcohol