6-Bromopyridine-2-carboxamide 98%

Base Information

• Chemical Name: 6-Bromopyridine-2-carboxamide 98%
• CAS No.: 25194-52-9
• Molecular Formula: C6H5BrN2O
• Molecular Weight: 201.023
• Hs Code.: 2933399090
• Mol file: 25194-52-9.mol

Synonyms:Picolinamide,6-bromo- (8CI);6-Bromo-2-pyridinecarboxamide;6-Bromopicolinamide;

Chemical Property of 6-Bromopyridine-2-carboxamide 98%

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 133-138°C
• Refractive Index: 1.614
• Boiling Point: 338.126 °C at 760 mmHg
• PKA: 14.45±0.50(Predicted)
• Flash Point: 158.293 °C
• PSA: 55.98000
• Density: 1.71 g/cm³
• LogP: 1.64330
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

6-Bromopyridine-2-carboxamide, 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 22-36/37/38
• Safety Statements: 26-28-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Bromopyridine-2-carboxamide 98%

There total 6 articles about 6-Bromopyridine-2-carboxamide 98% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6-bromo-pyridine-2-carboxylic acid (21190-87-4) → 6-bromo-pyridine-2-carboxylic acid amide (25194-52-9)

Guidance literature:

With ammonium chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; at 20 ℃;

Reference yield:

6-bromopyridin-2-carbonitrile (122918-25-6) → 6-bromo-pyridine-2-carboxylic acid amide (25194-52-9)

Guidance literature:

With Rhodococcus rhodochrous ATCC BAA 870 cobalt nitrile hydratase; In aq. buffer; at 30 ℃; pH=7.6; Enzymatic reaction;

DOI:10.3390/molecules25010238

Reference yield:

6-bromopyridine-2-carbonyl chloride (139487-69-7) → 6-bromo-pyridine-2-carboxylic acid amide (25194-52-9)

Guidance literature:

With ammonia; In 1,4-dioxane;

upstream raw materials:

methyl 6-Bromopicolinate

6-bromo-pyridine-2-carboxylic acid

6-bromopyridine-2-carbonyl chloride

1,1'-carbonyldiimidazole

Downstream raw materials:

6-bromopyridin-2-carbonitrile

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