2,3-Difluoro-4-(heptylo

Base Information

• Chemical Name: 2,3-Difluoro-4-(heptylo
• CAS No.: 122265-95-6
• Molecular Formula: C14H18 F2 O3
• Molecular Weight: 272.29
• Mol file: 122265-95-6.mol

Synonyms:2,3-Difluoro-4-(heptyloxy)benzoicacid

Chemical Property of 2,3-Difluoro-4-(heptylo

Chemical Property:

• PSA: 46.53000
• LogP: 4.01220

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-Difluoro-4-(heptylo

There total 4 articles about 2,3-Difluoro-4-(heptylo which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

2,3-difluoro-4-(heptyloxy)-acetophenone (122265-89-8) → 2,3-difluoro-4-(heptyloxy)benzoic acid (122265-95-6)

Guidance literature:

With bromine; In 1,4-dioxane; sodium hydroxide; 1.) rt, 30 min; 2.) 50 deg C, 30 min;

DOI:10.1002/hlca.19890720319

Reference yield:

1-Bromoheptane (629-04-9) → 2,3-difluoro-4-(heptyloxy)benzoic acid (122265-95-6)

Guidance literature:

Multi-step reaction with 3 steps

1: KOH / ethanol

2: FeCl₃ / CH₂Cl₂

3: Br₂; aq. NaOH / dioxane

With potassium hydroxide; sodium hydroxide; bromine; iron(III) chloride; In 1,4-dioxane; ethanol; dichloromethane;

DOI:10.1039/b201467j

Reference yield:

2,3-difluorophenol (6418-38-8) → 2,3-difluoro-4-(heptyloxy)benzoic acid (122265-95-6)

Guidance literature:

Multi-step reaction with 3 steps

1: KOH / ethanol

2: FeCl₃ / CH₂Cl₂

3: Br₂; aq. NaOH / dioxane

With potassium hydroxide; sodium hydroxide; bromine; iron(III) chloride; In 1,4-dioxane; ethanol; dichloromethane;

DOI:10.1039/b201467j

upstream raw materials:

2,3-difluoro-4-(heptyloxy)-acetophenone

1-Bromoheptane

2,3-difluorophenol

2,3-difluoro-4-(heptyloxy)benzene