(S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one

Base Information

Chemical Name:(S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one
CAS No.:122151-38-6
Molecular Formula:C7H13 N O2
Molecular Weight:143.186
Hs Code.:2933990090
European Community (EC) Number:601-833-8,928-364-4
DSSTox Substance ID:DTXSID30453323
Nikkaji Number:J1.383.887I
Wikidata:Q76416536
Mol file:122151-38-6.mol

Synonyms:122151-38-6;(S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one;1-[(2S-)-2-Hydroxy-1-oxo-proxyl]pyrrolidine;(2S)-2-Hydroxy-1-pyrrolidin-1-ylpropan-1-one;Pyrrolidine, 1-[(2S)-2-hydroxy-1-oxopropyl]-;(2S)-2-hydroxy-1-(pyrrolidin-1-yl)propan-1-one;(2S)-2-hydroxy-1-pyrrolidin-1-yl-propan-1-one;SCHEMBL3288873;DTXSID30453323;KLCGBSXTJWOEJD-LURJTMIESA-N;MFCD12912701;AKOS016008166;AS-68113;(S)-1-Pyrrolizino-2-hydroxy-1-propanone;CS-0059827;1-Propanone, 2-hydroxy-1-(1-pyrrolidinyl)-, (2S)-

Suppliers and Price of (S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one 97%
5g
$ 356.00

Crysdot
(S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one 97%
10g
$ 570.00

Chemenu
(S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one 97%
10g
$ 533.00

Chemenu
(S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one 97%
5g
$ 333.00

American Custom Chemicals Corporation
(S)-2-HYDROXY-1-(PYRROLIDIN-1-YL)PROPAN-1-ONE 95.00%
1G
$ 329.70

AK Scientific
(S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one
1g
$ 411.00

AK Scientific
(S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one
5g
$ 1131.00

AccelPharmtech
1(2S)(2-HYDROXY-1-OXOPROPYL)PYRROLIDINE 97.00%
25G
$ 2080.00

AccelPharmtech
1(2S)(2-HYDROXY-1-OXOPROPYL)PYRROLIDINE 97.00%
5G
$ 1130.00

AccelPharmtech
1(2S)(2-HYDROXY-1-OXOPROPYL)PYRROLIDINE 97.00%
1G
$ 1020.00

Total 40 raw suppliers

Chemical Property of (S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.507
Boiling Point:282.498°C at 760 mmHg
PKA:13.65±0.20(Predicted)
Flash Point:124.651°C
PSA：40.54000
Density:1.142g/cm³
LogP:-0.07250
Storage Temp.:2-8°C
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:143.094628657
Heavy Atom Count:10
Complexity:130

Purity/Quality:

99.9% ^*data from raw suppliers

(S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)N1CCCC1)O
Isomeric SMILES:C[C@@H](C(=O)N1CCCC1)O
General Description 1-[(2S)-2-Hydroxy-1-oxopropyl]pyrrolidine, also known by its various synonyms, is a chiral auxiliary derived from (S)-lactic acid and pyrrolidine. It has been utilized in the stereoselective synthesis of arylpropionic and aryloxy acids, demonstrating good asymmetric induction in esterification and substitution reactions. 1-[(2S-)-2-Hydroxy-1-oxo-proxyl]pyrrolidine facilitates dynamic kinetic resolution and diastereoselective coupling, particularly in the synthesis of 2-aryloxy acids from racemic α-halo carboxylic acids, enhancing both reaction rates and stereoselectivity. Its effectiveness as a chiral auxiliary highlights its utility in asymmetric synthetic methodologies.

Technology Process of (S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one

There total 4 articles about (S)-2-Hydroxy-1-(pyrrolidin-1-yl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%