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Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II), also known as Ruthenium(II) chloride, is a transition metal complex with the chemical formula [CpRu(PPh3)2Cl]. It is an orange powder and is known for its catalytic properties in various chemical reactions.

32993-05-8

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32993-05-8 Usage

Uses

Used in Pharmaceutical Industry:
Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II) is used as a catalyst in the synthesis of various pharmaceutical compounds, such as indoles, isoquinolines, and quinolines. These compounds are important building blocks for the development of new drugs and have potential applications in the treatment of various diseases.
Used in Chemical Synthesis:
In the field of chemical synthesis, Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II) is used as an efficient transfer hydrogenation catalyst. This application is crucial for the production of various organic compounds, as it allows for the selective reduction of functional groups without the need for external hydrogen sources.
Used in Research and Development:
Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II) is also utilized in research and development for the study of catalytic mechanisms and the development of new catalytic systems. Its unique properties make it a valuable tool for understanding and improving the efficiency of various chemical reactions.

Check Digit Verification of cas no

The CAS Registry Mumber 32993-05-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,9,9 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 32993-05:
(7*3)+(6*2)+(5*9)+(4*9)+(3*3)+(2*0)+(1*5)=128
128 % 10 = 8
So 32993-05-8 is a valid CAS Registry Number.
InChI:InChI=1/2C18H15P.C5H5.ClH.Ru/c2*1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;1-2-4-5-3-1;;/h2*1-15H;1-5H;1H;/q;;;;-1/p+1/rC41H37ClP2Ru/c42-45(41-33-19-20-34-41,43(35-21-7-1-8-22-35,36-23-9-2-10-24-36)37-25-11-3-12-26-37)44(38-27-13-4-14-28-38,39-29-15-5-16-30-39)40-31-17-6-18-32-40/h1-34,41,43-44H

32993-05-8 Well-known Company Product Price

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  • TCI America

  • (C2201)  Cyclopentadienylbis(triphenylphosphine)ruthenium(II) Chloride  

  • 32993-05-8

  • 1g

  • 690.00CNY

  • Detail
  • TCI America

  • (C2201)  Cyclopentadienylbis(triphenylphosphine)ruthenium(II) Chloride  

  • 32993-05-8

  • 5g

  • 2,490.00CNY

  • Detail
  • Alfa Aesar

  • (46430)  Chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium(II) ethanol adduct   

  • 32993-05-8

  • 1g

  • 755.0CNY

  • Detail
  • Alfa Aesar

  • (46430)  Chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium(II) ethanol adduct   

  • 32993-05-8

  • 5g

  • 2960.0CNY

  • Detail
  • Aldrich

  • (333158)  Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II)  

  • 32993-05-8

  • 333158-1G

  • 810.81CNY

  • Detail

32993-05-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name Chlorocyclopentadienylbis(triphenylphosphine)ruthenium(II)

1.2 Other means of identification

Product number -
Other names CpRu(PPh3)2Cl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32993-05-8 SDS

32993-05-8Relevant academic research and scientific papers

A VERSATILE ROUTE TO (η5-C5R5)RuL2X FROM ALLYLMETHYLRUTHENIUM COMPLEXES

Nagashima, Hideo,Yamaguchi, Keitaro,Mukai, Katsunori,Itoh, Kenji

, p. C20 - C22 (1985)

Divalent ruthenium complexes, (η5-C5R5)RuL2X (R=H, CH3; X=Br, Cl), are formed by thermal decomposition of (η5-C5R5)Ru(CH3)X(η3-C3H5) in the presence of several neutral ligands.

Cyclopentadienyl-ruthenium and -osmium complexes VII. Formation and properties of ion-pairs containing the dihydride (η-cyclopentadienyl)bis(triphenylphosphine)-ruthenium(IV) cation

Wilczewski, Tadeusz

, p. 219 - 230 (1989)

The + cation in the simple and fast reaction of CpRuH(PPh3)2 with organic sulphonic acids in polar solvents (methanol, acetone) has been obtained in the form of ion-pairs.The reaction runs for several minutes, with practically quantitative yields.The dihydride complex cation obtained may be isolated from polar solutions as a sparingly soluble ion-pair with the tetraphenylborate anion.In the ion-pairs a reduction-elimination process slowly proceeds with the formation of non-ionic compounds of the CpRu(sulphonate)(PPh3)2 type.Also, the effect of methyl substituents in the Cp-ring on shifts in the 31P NMR signals and MS(FD) investigations of the new compounds obtained have been described.Explanation of the new group signals in the MS(FD) spectra as originating from the fragments formed, containing two ruthenium atoms ?-bonded to the phenyl ring of BPh4, i.e. 6-C6H5)BPh2CpRu(η6-C6H5)>+, were proposed.In the case of compounds containing the PPh3 molecule, a similar phenomenon occurs.For fragments obtained in the MS(FD) spectra, the formula 6-C6H5)>+ was ascribed.

A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites

Rodríguez Arce, Esteban,Sarniguet, Cynthia,Moraes, Tania S.,Vieites, Marisol,Tomaz, A. Isabel,Medeiros, Andrea,Comini, Marcelo A.,Varela, Javier,Cerecetto, Hugo,González, Mercedes,Marques, Fernanda,García, M. Helena,Otero, Lucía,Gambino, Dinorah

, p. 2923 - 2937 (2015)

(Chemical Equation Presented). As part of our efforts to develop organometallic ruthenium compounds bearing activity on both trypanosomatid parasites and tumor cells, a new Ru(II)-cyclopentadienyl clotrimazole complex, [RuCp(PPh3)2(C

Reactions of Transition Metal ?-Acetylides VIII. Preparation and Properties of some Aryldiazo-vinylidene Complexes

Bruce, Michael I.,Humphrey, Mark G.,Liddell, Michael J.

, p. 91 - 102 (1987)

Fourteen aryldiazovinylidene complexes of ruthenium and osmium have been made by addition of aryldiazonium cations to the appropriate ?-acetylides.Their properties and spectra (including FAB-MS) are described, and reactions with MeOH, hydride and methoxid

The Kinatics of the Reaction of with Various Olefins

Alibrandi, Giuseppe,Mann, Brian E.

, p. 951 - 954 (1994)

A detailed kinetic investigation of the reaction of with cycloheptatriene, cyclohepta-1,3-diene, cyclooctatetraene, penta-1,4-diene, cycloocta-1,5-diene and dimethyl maleate, has been carried out spectrophotometrically in CH2Cl2 at 10 deg C.It is shown that the major mechanism is via dissociation of PPh3 to give which then reacts with the olefin.There is also a second mechanism involving direct attack of the olefin on .

Polymorphism and thermodynamic properties of chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium(II) complex

Gorbachuk, Elena V.,Badeeva, Elena K.,Zinnatullin, Ruzal G.,Pavlov, Pavel O.,Dobrynin, Alexey B.,Gubaidullin, Aidar T.,Ziganshin, Marat A.,Gerasimov, Alexander V.,Sinyashin, Oleg G.,Yakhvarov, Dmitry G.

, p. 49 - 53 (2016)

A new crystalline polymorph of known chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium(II) complex [RuCl(PPh3)2(η5-C5H5)] was obtained and characterized by various analytical methods including

Kinetics of phosphine substitution in CpRu(PPh3)2X (X = Cl, Br, I, N3, and NCO)

Hill, David,Delaney, Connor,Clark, Miles,Eaton, Mathew,Hassan, Bakar,Hendricks, Olivia,Dang, Duy Khoi,Kirss, Rein U.

, p. 34425 - 34434 (2017)

The kinetics of phosphine substitution in CpRu(PPh3)2X (X = Br, 1b, X = I, 1c, X = N3, 1d, and X = NCO, 1e) have been measured under pseudo-first order conditions in THF solution and compared with data for CpRu(PPh3)2X (1a). The relative rate of substitution is found to be 1a > 1d > 1b > 1e > 1c. Substitution rates decrease in the presence of added PPh3 and are independent of added X consistent with a dissociative process. Activation parameters for 1a-1c (ΔH? = 113-135 kJ mol-1, ΔS? = 21-102 J mol-1 K-1) and DFT calculations support a dissociative or dissociative interchange pathway even though negative activation entropies (ΔS? = -48 ± 16 to -105 ± 5 J mol-1 K-1) are observed for 1d-e. Differences in Ru-ligand bond angles in 1d-e point to different π-acceptor properties of the pseudohalide ligands, contributing to the faster rate of substitution for the azide complexes, 1d relative to the cyanate derivative 1e. Substitution is not observed when X = F, 1f, X = H, 1g, X = SnF3, 1h, or X = SnCl3, 1i. Compounds 1b-1e also react with chloroform to yield 1a. The rates of halide exchange are comparable to phosphine substitution for 1c and 1d. The latter reaction is inhibited by excess triphenylphosphine and is unaffected by both radical inhibitors and radical traps suggesting that a radical mechanism is unlikely.

Solvent- A nd anion-dependent rearrangement of fluorinated carbene ligands provides access to fluorinated alkenes

Hall, Lewis M.,Milner, Lucy M.,Hart, Sam J.,Whitwood, Adrian C.,Lynam, Jason M.,Slattery, John M.

supporting information, p. 17655 - 17659 (2019/12/23)

The construction of fluorocarbene ligands within the coordination sphere of transition metal complexes using sequential nucleophilic and electrophilic addition to a vinylidene complex is described. Reaction of [Ru(η5-C5H5)(dppe)(CCPhF)][N(SO2Ph)2] with [NMe4]F results in nucleophilic attack of fluoride at the metal-bound carbon of the vinylidene ligand to give alkenyl complex [Ru(η5-C5H5)(dppe)(-CFCFPh)]. Subsequent eletrophilic fluorination with N-fluorobenzenesulfonimide (NFSI) results in the formation of the fluorinated carbene complex [Ru(η5-C5H5)(dppe)(CF-CHFPh)][N(SO2Ph)2]. The fluorocarbene complexes undergo rearrangement to liberate free fluorinated alkenes, a process governed by the choice of solvent and anion, representing a new metal-mediated route to fluorinated alkenes from alkynes.

Tandem transfer hydrogenation-epoxidation of ketone substrates catalysed by alkene-tethered Ru(ii)-NHC complexes

Malan, Frederick P.,Singleton, Eric,Van Rooyen, Petrus H.,Landman, Marilé

, p. 8472 - 8481 (2019/06/14)

A series of nine cyclopentadienyl Ru(ii)-NHC complexes (1-9) have been synthesised by systematically varying the ligand and/or ligand substituents: η5-C5H4R′ (R′ = H, Me), EPh3 (E = P, As), NHC (Im, BIm), where NHC = Im(R)(R′) (R, R′ = Me, Bn, 4-NO2Bn, C2H4Ph, C4H7). Each of the Ru(ii)-NHC complexes features an N-alkenyl tether to attain bidentate NHC ligands. All complexes found application as catalysts in the tandem transfer hydrogenation and epoxidation reactions of carbonyl substrates. The catalytic activity of the complexes was shown to be similar, with efficiencies of up to 69% conversion after 18 hours and varying alcohol:epoxide selectivity for a variety of electronically diverse carbonyl substrates. Complex 3, with a nitro-containing substituent on the NHC ligand, was the only complex that showed preference for the alcohol product over the epoxide after 18 hours of reaction time.

Syntheses of transition metal methoxysiloxides

Richers, Casseday P.,Bertke, Jeffery A.,Rauchfuss, Thomas B.

supporting information, p. 8756 - 8762 (2017/07/22)

The paper describes three methods for the preparation of methoxysiloxide complexes, a rare class of complexes of relevance to room temperature vulcanization (RTV) of polysiloxanes. The salt metathesis reaction involves the use of the recently described re

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