(Z)-3,3-bis(trimethylsilyl)prop-1-enyl phenyl ketone

Base Information

• Chemical Name: (Z)-3,3-bis(trimethylsilyl)prop-1-enyl phenyl ketone
• CAS No.: 78375-57-2
• Molecular Formula: C₁₆H₂₆OSi₂
• Molecular Weight: 290.553
• Mol file: 78375-57-2.mol

Synonyms:(Z)-3,3-bis(trimethylsilyl)prop-1-enyl phenyl ketone

Chemical Property of (Z)-3,3-bis(trimethylsilyl)prop-1-enyl phenyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-3,3-bis(trimethylsilyl)prop-1-enyl phenyl ketone

There total 5 articles about (Z)-3,3-bis(trimethylsilyl)prop-1-enyl phenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-benzoyloxy-4,4-bis(trimethylsilyl)-1-phenylbutadiene (78375-56-1) → (Z)-3,3-bis(trimethylsilyl)prop-1-enyl phenyl ketone (78375-57-2)

Guidance literature:

With methyllithium; In tetrahydrofuran; diethyl ether; at 0 ℃; for 2h;

DOI:10.1039/P19810000969

Reference yield:

tris(trimethylsilyl)methyllithium (28830-22-0) → (Z)-3,3-bis(trimethylsilyl)prop-1-enyl phenyl ketone (78375-57-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 132 mg / tetrahydrofuran / 2 h / Heating

2: 80 percent / methyl lithium / diethyl ether; tetrahydrofuran / 2 h / 0 °C

With methyllithium; In tetrahydrofuran; diethyl ether;

DOI:10.1039/P19810000969

Reference yield:

benzoyl chloride (98-88-4) → (Z)-3,3-bis(trimethylsilyl)prop-1-enyl phenyl ketone (78375-57-2)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran

2: 1.) lithium / 1.) ether, overnight, 2.) 2 h, room temperature

3: 80 percent / methyl lithium / diethyl ether; tetrahydrofuran / 2 h / 0 °C

With methyllithium; lithium; In tetrahydrofuran; diethyl ether;

DOI:10.1039/P19810000969

upstream raw materials:

1-benzoyloxy-4,4-bis(trimethylsilyl)-1-phenylbutadiene

tris(trimethylsilyl)methyllithium

benzoyl chloride

benzonitrile

Downstream raw materials:

(E)-1-phenyl-2-buten-1-one

Refernces