dimethyl-2-[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]silanol

Base Information

• Chemical Name: dimethyl-2-[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]silanol
• CAS No.: 861392-00-9
• Molecular Formula: C₁₉H₂₈O₆Si
• Molecular Weight: 380.513
• Mol file: 861392-00-9.mol

Synonyms:dimethyl-2-[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]silanol

Chemical Property of dimethyl-2-[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]silanol

Chemical Property:

Purity/Quality:

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Technology Process of dimethyl-2-[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]silanol

There total 1 articles about dimethyl-2-[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]silanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

diethyl (1-dimethyl[phenyl]silylvinyl)(3-methoxybenzyl)malonate (861391-99-3) → dimethyl-2-[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]silanol (861392-00-9) + 1,1,3,3-tetramethyl-1,3-di[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]disiloxane (861392-01-0)

Guidance literature:

diethyl (1-dimethyl[phenyl]silylvinyl)(3-methoxybenzyl)malonate; With trifluorormethanesulfonic acid; In dichloromethane; at -10 ℃; for 0.166667h;

With ammonium hydroxide; In dichloromethane; Further stages.;

DOI:10.1002/ejoc.200700440

Reference yield: 80.0%

dimethyl-2-[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]silanol (861392-00-9) + 1,1,3,3-tetramethyl-1,3-di[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]disiloxane (861392-01-0) + para-iodoanisole (696-62-8) → ethyl (E)-2-ethoxycarbonyl-2-(3-methoxybenzyl)-4-(4-methoxyphenyl)-3-butenoate

Guidance literature:

With tetrabutyl ammonium fluoride; tetrabutyl-ammonium chloride; triethylamine; bis(η3-allyl-μ-chloropalladium(II)); In N,N-dimethyl-formamide; at 80 ℃; for 40h;

DOI:10.1016/j.tetlet.2005.05.050

Reference yield: 75.0%

dimethyl-2-[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]silanol (861392-00-9) + 1,1,3,3-tetramethyl-1,3-di[3,3-diethoxycarbonyl-4-(3-methoxyphenyl)-1-butenyl]disiloxane (861392-01-0) + 4-Acetamido-1-iodobenzene (622-50-4) → ethyl (E)-4-(4-acetamidophenyl)-2-ethoxycarbonyl-2-(3-methoxybenzyl)-3-butenoate

Guidance literature:

With tetrabutyl ammonium fluoride; tetrabutyl-ammonium chloride; triethylamine; bis(η3-allyl-μ-chloropalladium(II)); In N,N-dimethyl-formamide; at 80 ℃; for 40h;

DOI:10.1016/j.tetlet.2005.05.050

upstream raw materials:

diethyl (1-dimethyl[phenyl]silylvinyl)(3-methoxybenzyl)malonate