[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester

Base Information

Chemical Name:[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester
CAS No.:1097069-22-1
Molecular Formula:C₁₅H₁₆F₃NO₄
Molecular Weight:331.292
Hs Code.:

Synonyms:[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester

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Chemical Property of [cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester

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Technology Process of [cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester

There total 1 articles about [cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 36823-88-8
4-(trifluoromethoxy)benzoyl chloride

: 71922-62-8
[(cyclopropyl)amino]acetic acid ethyl ester

: 1097069-22-1
[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester

Guidance literature:: With sodium hydrogencarbonate; In dichloromethane; for 1h;

Reference yield: 58.0%

: 59-67-6
nicotinic acid

: 1097069-22-1
[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester

: 1097069-26-5
2-[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-3-oxo-3-pyridin-3-yl-propionic acid ethyl ester

Guidance literature:: [cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - -30 ℃; for 1h;

nicotinic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; dichloromethane; for 1h;

[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester; In tetrahydrofuran; at -30 - 20 ℃; for 2h;

Reference yield: 13.0%

: 1097069-22-1
[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester

: 108-24-7
acetic anhydride

: 1097069-23-2
2-[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-3-oxo-butyric acid ethyl ester

Guidance literature:: [cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-acetic acid ethyl ester; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h;

acetic anhydride; In tetrahydrofuran; at 20 ℃; for 2h;