2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester

Base Information

Chemical Name:2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester
CAS No.:103825-45-2
Molecular Formula:C₁₈H₂₄N₂O₄
Molecular Weight:332.4
Hs Code.:

Synonyms:2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester

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Chemical Property of 2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester

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Technology Process of 2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester

There total 2 articles about 2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.7%

: 98-88-4
benzoyl chloride

: 2-<(2RS,4S)-2-(tert-Butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester

: 103825-45-2
2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester

: 103825-42-9
2-<(2S,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester

Guidance literature:: With triethylamine; In dichloromethane; 1.) 0 deg C 45 min; 2.) room temperature 12 h;
DOI:10.1002/hlca.19850680603

Reference yield:

: 630-19-3
pivalaldehyde

: 103825-45-2
2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester

Guidance literature:: Multi-step reaction with 2 steps

2: 12.3 percent / Et₃N / CH₂Cl₂ / 1.) 0 deg C 45 min; 2.) room temperature 12 h

With triethylamine; In dichloromethane;
DOI:10.1002/hlca.19850680603

Reference yield: 95.5%

: 103825-45-2
2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure-methylester

: 103825-48-5
2-<(2R,4S)-3-Benzoyl-2-(tert-butyl)-1-methyl-5-oxoimidazolidin-4-yl>essigsaeure

Guidance literature:: With potassium hydroxide; In methanol; water; 1.) 0 deg C, 15 min; 2.) room temperature, 10 h;
DOI:10.1002/hlca.19850680603