5-[(4-Hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide

Base Information

Chemical Name:5-[(4-Hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide
CAS No.:63033-36-3
Molecular Formula:C₁₀H₉NO₅S₃
Molecular Weight:319.383
Hs Code.:
ChEMBL ID:CHEMBL172065
DSSTox Substance ID:DTXSID201332511

Synonyms:63033-36-3;2-thiophenesulfonamide,5-[(4-hydroxyphenyl)sulfonyl]-;CHEMBL172065;SCHEMBL9831469;GXOBTQMAAWWKKU-UHFFFAOYSA-N;DTXSID201332511;FT-0748686;5-(4-hydroxyphenyl)sulfonylthiophene-2-sulfonamide;5-[(4-hydroxyphenyl)sulfonyl]-thiophene-2-sulfonamide;5-[(4-hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide

Suppliers and Price of 5-[(4-Hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[(4-Hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:318.96428591
Heavy Atom Count:19
Complexity:510

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1O)S(=O)(=O)C2=CC=C(S2)S(=O)(=O)N

Technology Process of 5-[(4-Hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide

There total 2 articles about 5-[(4-Hydroxyphenyl)sulfonyl]thiophene-2-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 63032-04-2
2-(p-hydroxyphenyl) thio-5-thiophenesulfonamide

: 63033-36-3
5-[(4-hydroxyphenyl)sulfonyl]-thiophene-2-sulfonamide

Guidance literature:: With dihydrogen peroxide; In acetic acid; for 1h; Heating;
DOI:10.1021/jm00140a009

Reference yield:

: 637-89-8
4-sulfanylphenol

: 63033-36-3
5-[(4-hydroxyphenyl)sulfonyl]-thiophene-2-sulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 51 percent / aq. NaOH / dimethylformamide / 4 h / Heating

2: 70 percent / 30percent H₂O₂ / acetic acid / 1 h / Heating

With sodium hydroxide; dihydrogen peroxide; In acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00140a009