ethyl 2-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-4-methyl-5-pyrimidinecarboxylate

Base Information

Chemical Name:ethyl 2-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-4-methyl-5-pyrimidinecarboxylate
CAS No.:940880-14-8
Molecular Formula:C₁₈H₁₄Cl₂F₃N₃O₃
Molecular Weight:448.229
Hs Code.:

Synonyms:ethyl 2-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-4-methyl-5-pyrimidinecarboxylate

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Chemical Property of ethyl 2-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-4-methyl-5-pyrimidinecarboxylate

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Technology Process of ethyl 2-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-4-methyl-5-pyrimidinecarboxylate

There total 1 articles about ethyl 2-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-4-methyl-5-pyrimidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 864725-22-4
1,3-dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzene

: 940880-13-7
ethyl 2-[(hydroxyimino)methyl]-4-methyl-5-pyrimidinecarboxylate

: 940880-14-8
ethyl 2-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-4-methyl-5-pyrimidinecarboxylate

Guidance literature:: With sodium hydroxide; sodium hypochlorite; In tetrahydrofuran; diethyl ether; water; at 5 - 20 ℃; for 1h;

Reference yield:

: 940880-14-8
ethyl 2-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-4-methyl-5-pyrimidinecarboxylate

: 2-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-4-methyl-5-pyrimidinecarboxylic acid

Guidance literature:: ethyl 2-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-4-methyl-5-pyrimidinecarboxylate; With sodium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 18h;

With hydrogenchloride; water; In tetrahydrofuran;