(+/-)-N-(t-butoxycarbonyl)-2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]-piperidine

Base Information

Chemical Name:(+/-)-N-(t-butoxycarbonyl)-2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]-piperidine
CAS No.:276872-82-3
Molecular Formula:C₂₃H₃₅FN₂O₂
Molecular Weight:390.542
Hs Code.:

Synonyms:(+/-)-N-(t-butoxycarbonyl)-2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]-piperidine

Suppliers and Price of (+/-)-N-(t-butoxycarbonyl)-2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]-piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (+/-)-N-(t-butoxycarbonyl)-2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]-piperidine

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Technology Process of (+/-)-N-(t-butoxycarbonyl)-2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]-piperidine

There total 4 articles about (+/-)-N-(t-butoxycarbonyl)-2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]-piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 276872-82-3
(+/-)-N-(t-butoxycarbonyl)-2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]-piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 1 h / 20 °C

2: tetrapropylammoniumperruthenate; NMO; 3 Angstroem molecular sieves / CH₂Cl₂ / 1 h

3: NaBH(OAc)3 / 1,2-dichloro-ethane

With N-methyl-2-indolinone; tetrapropylammonium perruthennate; 3 A molecular sieve; sodium tris(acetoxy)borohydride; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1016/S0960-894X(02)00206-8

Reference yield:

: 157634-00-9
tert-butyl 2-(hydroxymethyl)piperidine-1-carboxylate

: 276872-82-3
(+/-)-N-(t-butoxycarbonyl)-2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]-piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrapropylammoniumperruthenate; NMO; 3 Angstroem molecular sieves / CH₂Cl₂ / 1 h

2: NaBH(OAc)3 / 1,2-dichloro-ethane

With N-methyl-2-indolinone; tetrapropylammonium perruthennate; 3 A molecular sieve; sodium tris(acetoxy)borohydride; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1016/S0960-894X(02)00206-8

Reference yield:

: 3433-37-2
piperidin-2-ylmethanol

: 276872-82-3
(+/-)-N-(t-butoxycarbonyl)-2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]-piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 1 h / 20 °C

2: tetrapropylammoniumperruthenate; NMO; 3 Angstroem molecular sieves / CH₂Cl₂ / 1 h

3: NaBH(OAc)3 / 1,2-dichloro-ethane

With N-methyl-2-indolinone; tetrapropylammonium perruthennate; 3 A molecular sieve; sodium tris(acetoxy)borohydride; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1016/S0960-894X(02)00206-8