methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester

Base Information

Chemical Name:methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester
CAS No.:365565-92-0
Molecular Formula:C₁₉H₂₂N₂O₃S
Molecular Weight:358.461
Hs Code.:

methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-<i>a</i>]pyridin-2-yl)-phenyl]-butyl ester

Synonyms:methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester

Suppliers and Price of methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester

There total 5 articles about methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 124-63-0
methanesulfonyl chloride

: 365565-91-9
4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butan-1-ol

: 365565-92-0
methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester

Guidance literature:: With triethylamine; In dichloromethane; for 18h;
DOI:10.1016/S0960-894X(02)00738-2

Reference yield:

: 695-34-1
2-Amino-4-methylpyridine

: 365565-92-0
methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 58 percent / ethanol / 18 h / Heating

2: 56 percent / CuI; Et₃N; Pd(PPh₃)4 / acetonitrile / 18 h / Heating

3: 100 percent / H₂ / 5 percent Pd/BaSO₄ / ethanol / 4.5 h

4: 100 percent / Et₃N / CH₂Cl₂ / 18 h

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen; triethylamine; Pd-BaSO₄; In ethanol; dichloromethane; acetonitrile; 2: Sonogashira coupling;
DOI:10.1016/S0960-894X(02)00738-2

Reference yield:

: 838-32-4
2-(4-bromophenyl)-7-methylimidazo[1,2-a]pyridine

: 365565-92-0
methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 56 percent / CuI; Et₃N; Pd(PPh₃)4 / acetonitrile / 18 h / Heating

2: 100 percent / H₂ / 5 percent Pd/BaSO₄ / ethanol / 4.5 h

3: 100 percent / Et₃N / CH₂Cl₂ / 18 h

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen; triethylamine; Pd-BaSO₄; In ethanol; dichloromethane; acetonitrile; 1: Sonogashira coupling;
DOI:10.1016/S0960-894X(02)00738-2