838-32-4

Basic information

• Product Name: 2-(4-BROMO-PHENYL)-7-METHYL-IMIDAZO[1,2-A]PYRIDINE
• Synonyms: 2-(4-BROMO-PHENYL)-7-METHYL-IMIDAZO[1,2-A]PYRIDINE
• CAS NO: 838-32-4
• Molecular Formula: C₁₄H₁₁BrN₂
• Molecular Weight: 287.15454
• Mol File: 838-32-4.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-BROMO-PHENYL)-7-METHYL-IMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-BROMO-PHENYL)-7-METHYL-IMIDAZO[1,2-A]PYRIDINE(838-32-4)
• EPA Substance Registry System: 2-(4-BROMO-PHENYL)-7-METHYL-IMIDAZO[1,2-A]PYRIDINE(838-32-4)

Safety Data

• Hazardous Substances Data: 838-32-4(Hazardous Substances Data)

Usage

Class

Imidazo[1,2-a]pyridine compounds It belongs to a specific group of organic compounds characterized by a pyridine ring fused to an imidazole ring.

Molecular structure

Pyridine ring fused to an imidazole ring The compound's core structure features a five-membered nitrogen-containing pyridine ring connected to a five-membered imidazole ring.

Usage

Building block and intermediate in synthesis It is commonly used as a building block and intermediate in the synthesis of pharmaceuticals, agrochemicals, and other biologically active compounds.

Importance in research

Valuable tool in medicinal chemistry and drug development The unique structure and properties of 2-(4-bromo-phenyl)-7-methyl-imidazo[1,2-a]pyridine make it a valuable tool for researchers in medicinal chemistry and drug development.

Upstream product

• 695-34-1 2-Amino-4-methylpyridine 
• 299456-72-7 1-(4-bromophenyl)ethanone O-acetyl oxime 
• 99-90-1 para-bromoacetophenone 
• 59862-55-4 p-bromoacetophenone oxime 
• 13466-41-6 4-methyl-1H-pyridin-2-one 
• 108-89-4 picoline 
• 99-73-0 para-bromophenacyl bromide 
• 136106-08-6 4-methyl-1-[2-(4-bromophenyl)-2-oxoethyl]pyridinium bromide 

Downstream Products

• 727652-08-6 C₁₅H₁₁BrN₂O 
• 118000-55-8 4-(7-Methyl-imidazo[1,2-a]pyridin-2-yl)-benzaldehyde 
• 365565-90-8 methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-but-3-ynyl ester 
• 365565-92-0 methanesulfonic acid 4-[4-(7-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-butyl ester 

Relevant articles and documents

Solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines by grindstone chemistry

The present work describes the solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines in excellent to nearly quantitative yields from 2-aminopyridines and a wide variety of ω-bromomethylketones using a grindstone procedure at 25°C to 30°C for 3 to

Rapid Construction of Fused Heteropolycyclic Aromatics via Palladium-Catalyzed Domino Arylations of Imidazopyridine Derivatives

By using diaryliodonium salts, a novel approach of a palladium-catalyzed cascade of diarylation/intramolecular dehydrogenative coupling reaction has been developed in the synthesis of phenanthro-imidazopyridine fused heteropolycycles. The method can toler

A synthetic method of 2-phenyl-imidazo[1,2-a]pyridine compounds

A synthetic method of 2-phenyl-imidazo[1,2-a]pyridine compounds is disclosed. Compared with the prior art, the method adopts a high-frequency mechanical grinding technique, is finished by a one-step reaction and is simple in operation, free of solvents in a reaction process and free of chemical agents with high toxicity. The method is short in reaction time and mild in reaction conditions, wherein the reaction can be finished in 90 min and can be performed at room temperature with a oscillation frequency of 30 Hz. The method is high in yield, and the highest yield can reach 94%. The method can rapidly and effectively synthesize the 2-phenyl-imidazo[1,2-a]pyridine compounds with strong electron withdrawing groups, while the 2-phenyl-imidazo[1,2-a]pyridine compounds with the strong electron withdrawing groups cannot be synthesized by traditional methods or are low in synthesis yield unless extremely extreme and strict reaction conditions are adopted.