(2S,4S,5S,7S)-4-amino-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)-8-methylnonyl isobutyrate

Base Information

Chemical Name:(2S,4S,5S,7S)-4-amino-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)-8-methylnonyl isobutyrate
CAS No.:1364791-13-8
Molecular Formula:C₃₄H₅₉N₃O₈
Molecular Weight:637.858
Hs Code.:

(2S,4S,5S,7S)-4-amino-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)-8-methylnonyl isobutyrate

Synonyms:(2S,4S,5S,7S)-4-amino-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)-8-methylnonyl isobutyrate

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Chemical Property of (2S,4S,5S,7S)-4-amino-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)-8-methylnonyl isobutyrate

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Technology Process of (2S,4S,5S,7S)-4-amino-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)-8-methylnonyl isobutyrate

There total 4 articles about (2S,4S,5S,7S)-4-amino-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)-8-methylnonyl isobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1315181-75-9
(2S,4S,5S,7S)-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-4-azido-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)-phenyl)-8-methylnonyl isobutyrate

: 1364791-13-8
(2S,4S,5S,7S)-4-amino-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)-8-methylnonyl isobutyrate

Guidance literature:: With ammonium formate; palladium 10% on activated carbon; In ethanol; water; for 48h;

Reference yield:

: 1257529-92-2
(3S,5S)-5-((1S,3S)-1-Azido-3-(hydroxy(4-methoxy-3-(3-methoxypropoxy)phenyl)methyl)-4-methylpentyl)-3-isopropyldihydrofuran-2(3H)-one

: 1364791-13-8
(2S,4S,5S,7S)-4-amino-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)-8-methylnonyl isobutyrate

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; triethylamine / toluene / 1 h / 20 °C

2: 88 °C

3: ammonium formate / palladium 10% on activated carbon / ethanol; water / 48 h

With dmap; ammonium formate; triethylamine; palladium 10% on activated carbon; In ethanol; water; toluene;

Reference yield:

: (2S,4S,5S,7S)-5-azido-4-hydroxy-7-(hydroxy(4-methoxy-3-(3-methoxypropoxy)phenyl)methyl)-2-isopropyl-8-methylnonanoic acid arginine salt

: 1364791-13-8
(2S,4S,5S,7S)-4-amino-7-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-5-hydroxy-2-isopropyl-1-(4-methoxy-3-(3-methoxypropoxy)phenyl)-8-methylnonyl isobutyrate

Guidance literature:: Multi-step reaction with 4 steps

1: citric acid / water; tert-butyl methyl ether / 1 h / pH 3

2: dmap; triethylamine / toluene / 1 h / 20 °C

3: 88 °C

4: ammonium formate / palladium 10% on activated carbon / ethanol; water / 48 h

With dmap; ammonium formate; triethylamine; citric acid; palladium 10% on activated carbon; In ethanol; tert-butyl methyl ether; water; toluene;