Benzeneacetic acid, 2,5-dibromo-, 3-bromophenyl ester

Base Information

• Chemical Name: Benzeneacetic acid, 2,5-dibromo-, 3-bromophenyl ester
• CAS No.: 1403991-82-1
• Molecular Formula: C₁₄H₉Br₃O₂
• Molecular Weight: 448.936
• Mol file: 1403991-82-1.mol

Synonyms:3-bromophenyl 2-(2,5-dibromophenyl)acetate

Chemical Property of Benzeneacetic acid, 2,5-dibromo-, 3-bromophenyl ester

Chemical Property:

• Boiling Point: 487.9±45.0 °C(Predicted)
• Density: 1.899±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Benzeneaceticacid,2,5-dibromo-,3-bromophenylester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzeneacetic acid, 2,5-dibromo-, 3-bromophenyl ester

There total 5 articles about Benzeneacetic acid, 2,5-dibromo-, 3-bromophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(2,5-dibromo-phenyl)-acetyl chloride (203314-51-6) + 3-Bromophenol (591-20-8) → 3-bromophenyl 2-(2,5-dibromophenyl)acetate (1403991-82-1)

Guidance literature:

With 2,6-dimethylpyridine; In dichloromethane; at 0 - 5 ℃; for 1h;

Reference yield: 91.0%

2-(2,5-dibromophenyl)-acetic acid (203314-28-7) + 3-Bromophenol (591-20-8) → 3-bromophenyl 2-(2,5-dibromophenyl)acetate (1403991-82-1)

Guidance literature:

2-(2,5-dibromophenyl)-acetic acid; With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 1.33333h; Inert atmosphere;

3-Bromophenol; With 2,6-dimethylpyridine; In dichloromethane; at 0 - 25 ℃; for 1h; Inert atmosphere;

Reference yield:

2-(2,5-dibromophenyl)-acetic acid (203314-28-7) → 3-bromophenyl 2-(2,5-dibromophenyl)acetate (1403991-82-1)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl dichloride / N,N-dimethyl-formamide; dichloromethane / 1 h / 20 °C / Inert atmosphere

2: 2,6-dimethylpyridine / dichloromethane / 1 h / 0 - 5 °C / Inert atmosphere

With 2,6-dimethylpyridine; oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ol500971c

upstream raw materials:

2-(2,5-dibromophenyl)-acetic acid

(2,5-dibromo-phenyl)-acetyl chloride

3-Bromophenol

1.4-dibromobenzene

Downstream raw materials:

1-(4-bromo-2-hydroxyphenyl)-2-(2,5-dibromophenyl)ethanone

5-bromo-2-(2-(2,5-dibromophenyl)-1-iminoethyl)phenol

(R)-2-(1-amino-2-(2,5-dibromophenyl)ethyl)-5-bromophenol

(R)-5-bromo-2-(5-bromoindolin-2-yl)phenol