203314-51-6

Basic information

• Product Name: (2,5-dibromo-phenyl)-acetyl chloride
• Synonyms: (2,5-dibromo-phenyl)-acetyl chloride
• CAS NO: 203314-51-6
• Molecular Weight: 312.388
• Mol File: 203314-51-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2,5-dibromo-phenyl)-acetyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (2,5-dibromo-phenyl)-acetyl chloride(203314-51-6)
• EPA Substance Registry System: (2,5-dibromo-phenyl)-acetyl chloride(203314-51-6)

Safety Data

• Hazardous Substances Data: 203314-51-6(Hazardous Substances Data)

Upstream product

• 610-71-9 2,5-dibromobenzoic acid 
• 642091-49-4 2,5-dibromobenzyl chloride 
• 74533-21-4 2-(2,5-dibromophenyl)acetonitrile 
• 203314-28-7 2-(2,5-dibromophenyl)-acetic acid 
• 147034-01-3 (2,5-dibromophenyl)methanol 

Relevant articles and documents

Hepatitis C virus inhibitor and application thereof

The invention relates to a hepatitis C virus inhibitor and application thereof, and particularly discloses a compound which can be used as a hepatitis C virus and is as shown in a formula (I), or optical isomer, pharmaceutically acceptable salt, hydrate or solvate thereof, which can be used for treating hepatitis C virus (HCV) infection or hepatitis C diseases, or used as a hepatitis C virus nonstructural 5A (NS5A) protein inhibitor.

Enantioselective synthesis of an HCV NS5a antagonist

A concise, enantioselective synthesis of the HCV NS5a inhibitor MK-8742 (1) is reported. The features of the synthesis include a highly enantioselective transfer hydrogenation of an NH imine and a dynamic diastereoselective transformation. The synthesis of this complex target requires simple starting materials and nine linear steps for completion.