1H-Pyrazolo[3,4-b]pyridine-6-carboxamide

Base Information

Chemical Name:1H-Pyrazolo[3,4-b]pyridine-6-carboxamide
CAS No.:116855-16-4
Molecular Formula:C₇H₆N₄O
Molecular Weight:162.151
Hs Code.:
DSSTox Substance ID:DTXSID10556422
Wikidata:Q82437966
Mol file:116855-16-4.mol

Synonyms:1H-Pyrazolo[3,4-b]pyridine-6-carboxamide;116855-16-4;1H-Pyrazolo[3,4-b]pyridine-6-carboxamide(9CI);SCHEMBL160552;DTXSID10556422

Suppliers and Price of 1H-Pyrazolo[3,4-b]pyridine-6-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
1H-Pyrazolo[3,4-b]pyridine-6-carboxamide 97.00%
5G
$ 3900.00

AccelPharmtech
1H-Pyrazolo[3,4-b]pyridine-6-carboxamide 97.00%
1G
$ 2280.00

Total 3 raw suppliers

Chemical Property of 1H-Pyrazolo[3,4-b]pyridine-6-carboxamide

Chemical Property:

Melting Point:290 °C(Solv: ethanol (64-17-5))
Boiling Point:437.2±55.0 °C(Predicted)
PKA:15.98±0.20(Predicted)
PSA：84.66000
Density:1.68±0.1 g/cm3(Predicted)
LogP:0.75710
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:162.05416083
Heavy Atom Count:12
Complexity:196

Purity/Quality:

97% ^*data from raw suppliers

1H-Pyrazolo[3,4-b]pyridine-6-carboxamide 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC2=C1C=NN2)C(=O)N

Technology Process of 1H-Pyrazolo[3,4-b]pyridine-6-carboxamide

There total 2 articles about 1H-Pyrazolo[3,4-b]pyridine-6-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 271-73-8
1H-Pyrazolo[3,4-b]pyridine

: 116855-16-4
1H-Pyrazolo[3,4-b]pyridine-6-carboxylic acid amide

Guidance literature:: With sulfuric acid; dihydrogen peroxide; iron(II) sulfate; at 10 - 15 ℃; for 0.5h;
DOI:10.1139/v88-074

Reference yield:

: 36404-88-3
2-chloro-3-carbaldehydepyridine

: 116855-16-4
1H-Pyrazolo[3,4-b]pyridine-6-carboxylic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: 25 percent / hydrazine hydrate / ethanol / 24 h / Heating

2: 25 percent / sulfuric acid, 30percent hydrogen peroxide, iron(II) sulfate heptahydrate / 0.5 h / 10 - 15 °C

With sulfuric acid; dihydrogen peroxide; hydrazine hydrate; iron(II) sulfate; In ethanol;
DOI:10.1139/v88-074