2-Chloro-3-formylpyridine

Base Information

Chemical Name:2-Chloro-3-formylpyridine
CAS No.:36404-88-3
Molecular Formula:C6H4ClNO
Molecular Weight:141.557
Hs Code.:29333990
European Community (EC) Number:629-217-4
DSSTox Substance ID:DTXSID40353269
Nikkaji Number:J735.783D
Wikidata:Q72458481
ChEMBL ID:CHEMBL2228156
Mol file:36404-88-3.mol

Synonyms:2-chloro-3-pyridinecarboxaldehyde

Suppliers and Price of 2-Chloro-3-formylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloronicotinaldehyde
50g
$ 690.00

TCI Chemical
2-Chloro-3-pyridinecarboxaldehyde >98.0%(GC)
5g
$ 57.00

TCI Chemical
2-Chloro-3-pyridinecarboxaldehyde >98.0%(GC)
1g
$ 19.00

SynQuest Laboratories
2-Chloronicotinaldehyde
5 g
$ 24.00

SynQuest Laboratories
2-Chloronicotinaldehyde
1 g
$ 18.00

SynQuest Laboratories
2-Chloronicotinaldehyde
10 g
$ 40.00

SynChem
2-Chloro-pyridine-3-carbaldehyde 95+%
5 g
$ 50.00

SynChem
2-Chloro-pyridine-3-carbaldehyde 95+%
1 g
$ 15.00

Sigma-Aldrich
2-Chloro-3-pyridinecarboxaldehyde 97%
1g
$ 31.90

Sigma-Aldrich
2-Chloro-3-pyridinecarboxaldehyde 97%
5g
$ 116.00

Total 111 raw suppliers

Chemical Property of 2-Chloro-3-formylpyridine

Chemical Property:

Appearance/Colour:white to light yellow crystal
Vapor Pressure:0.034mmHg at 25°C
Melting Point:50-54 °C(lit.)
Refractive Index:1.593
Boiling Point:242.264 °C at 760 mmHg
PKA:-1.36±0.10(Predicted)
Flash Point:100.318 °C
PSA：29.96000
Density:1.332 g/cm³
LogP:1.54750
Storage Temp.:Room temperature.
Solubility.:Chloroform, DMSO
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:140.9981414
Heavy Atom Count:9
Complexity:107

Purity/Quality:

99% ^*data from raw suppliers

2-Chloronicotinaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn, Xi
Hazard Codes:Xn,Xi
Statements: 22-36-43
Safety Statements: 26-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(N=C1)Cl)C=O
Uses Starting material for the preparation of 5-azaindoles by the Hemetsberger-Knittel reaction involving the thermal decomposition of alkenyl azides.1 Azaindazole intermediate. Starting material for the preparation of 5-azaindoles by the Hemetsberger-Knittel reaction involving the thermal decomposition of alkenyl azides.

Technology Process of 2-Chloro-3-formylpyridine

There total 20 articles about 2-Chloro-3-formylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.9%

: 42330-59-6
(2-chloropyrid-3-yl)methanol

: 36404-88-3
2-chloro-3-carbaldehydepyridine

Guidance literature:: With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In dichloromethane; at 0 - 20 ℃; for 1h; pH=11; Solvent;

Reference yield: 92.0%

: 36404-88-3
2-chloro-3-carbaldehydepyridine

Guidance literature:: With sulfuric acid; lithium acetate; water; silver; fluorosulphonic acid; acetic acid; In methanol; at 55 - 60 ℃; Electrolysis;

Reference yield: 57.0%

: 109-09-1
2-chloropyridine

: 109-94-4
formic acid ethyl ester

: 36404-88-3
2-chloro-3-carbaldehydepyridine

Guidance literature:: 2-chloropyridine; With 2,2,6,6-tetramethylpiperidinyl-lithium; In tetrahydrofuran; at -78 ℃; for 2.58333h;

formic acid ethyl ester; In tetrahydrofuran; at -78 - -40 ℃; for 0.5h;
DOI:10.1016/j.bmc.2014.12.011