(S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine

Base Information

Chemical Name:(S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine
CAS No.:62370-16-5
Molecular Formula:C₁₄H₂₂N₂
Molecular Weight:218.342
Hs Code.:
DSSTox Substance ID:DTXSID401024415

Synonyms:SCHEMBL4127495;CCXFKJBMYLLRBW-ZDUSSCGKSA-N;DTXSID401024415;(S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine;2-[2-[(2S)-1-Methyl-2-piperidinyl]ethyl]benzenamine;62370-16-5

Suppliers and Price of (S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:218.178298710
Heavy Atom Count:16
Complexity:205

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1CCCCC1CCC2=CC=CC=C2N
Isomeric SMILES:CN1CCCC[C@H]1CCC2=CC=CC=C2N

Technology Process of (S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine

There total 8 articles about (S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1360685-63-7
(S)-[2-(o-aminophenethyl)-1-methylpiperidine dibenzoyl-L-tartrate]

: 62370-16-5
(S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine

Guidance literature:: With sodium hydrogencarbonate; In ethyl acetate;
DOI:10.1021/op5003402

Reference yield:

: 62414-73-7
(S)-2-[2-(1-methyl-2-piperidinyl)ethyl]benzenamine (1R,3S)-(+)-camphoric acid salt

: 62370-16-5
(S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine

Guidance literature:: With sodium hydroxide; In Isopropyl acetate; water; at 20 - 30 ℃; for 0.166667 - 0.583333h; Product distribution / selectivity;

Reference yield:

: 77340-84-2
2-(o-nitrostyryl)-pyridine

: 62370-16-5
(S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine

Guidance literature:: Multi-step reaction with 4 steps

1.1: methyl iodide / acetone / Reflux

2.1: hydrogen; platinum on activated charcoal / methanol / 25 °C

3.1: sodium hydroxide / MeOH / 25 °C

3.2: 25 °C

4.1: sodium hydrogencarbonate / ethyl acetate

With platinum on activated charcoal; hydrogen; sodium hydrogencarbonate; sodium hydroxide; methyl iodide; In methanol; MeOH; ethyl acetate; acetone;
DOI:10.1021/op5003402