(E)-3-cyclohexylbut-2-enal

Base Information

• Chemical Name: (E)-3-cyclohexylbut-2-enal
• CAS No.: 91055-75-3
• Molecular Formula: C₁₀H₁₆O
• Molecular Weight: 152.236
• Mol file: 91055-75-3.mol

Synonyms:(E)-3-cyclohexylbut-2-enal

Chemical Property of (E)-3-cyclohexylbut-2-enal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-cyclohexylbut-2-enal

There total 4 articles about (E)-3-cyclohexylbut-2-enal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-cyclohexylbut-2-en-1-ol (131719-67-0) → (E)-3-cyclohexylbut-2-enal (91055-75-3) + (Z)-3-cyclohexylbut-2-enal

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 23 ℃; for 0.5h; Title compound not separated from byproducts;

DOI:10.1021/ja043834g

Reference yield:

(E)-ethyl 3-cyclohexylbut-2-enoate (28811-79-2,73232-03-8,73232-02-7) → (E)-3-cyclohexylbut-2-enal (91055-75-3)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether / 0.08 h / 0 °C

2: Dess-Martin periodinane / CH₂Cl₂ / 0.5 h / 23 °C

With lithium aluminium tetrahydride; Dess-Martin periodane; In diethyl ether; dichloromethane;

DOI:10.1021/ja043834g

Reference yield:

Cyclohexyl methyl ketone (823-76-7) → (E)-3-cyclohexylbut-2-enal (91055-75-3)

Guidance literature:

Multi-step reaction with 2 steps

1: liquid ammonia

2: water

With ammonia; water;

DOI:10.1080/08964280109595775

upstream raw materials:

formic acid

2-cyclohexylbut-3-yn-2-ol

(E)-3-cyclohexylbut-2-en-1-ol

(E)-ethyl 3-cyclohexylbut-2-enoate

Downstream raw materials:

(3R)-3-cyclohexylbutanal

(3S)-3-cyclohexylbutanal

3-cyclohexylbutanal