5-Ethyl-5-((1S,2S)-2-hydroxy-1,3,3-trimethyl-4-phenyl-butyl)-5H-dibenzophospholium; iodide

Base Information

• Chemical Name: 5-Ethyl-5-((1S,2S)-2-hydroxy-1,3,3-trimethyl-4-phenyl-butyl)-5H-dibenzophospholium; iodide
• CAS No.: 113686-97-8
• Molecular Formula: C₂₇H₃₂OP*I
• Molecular Weight: 530.429
• Mol file: 113686-97-8.mol

Synonyms:5-Ethyl-5-((1S,2S)-2-hydroxy-1,3,3-trimethyl-4-phenyl-butyl)-5H-dibenzophospholium; iodide

Chemical Property of 5-Ethyl-5-((1S,2S)-2-hydroxy-1,3,3-trimethyl-4-phenyl-butyl)-5H-dibenzophospholium; iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Ethyl-5-((1S,2S)-2-hydroxy-1,3,3-trimethyl-4-phenyl-butyl)-5H-dibenzophospholium; iodide

There total 10 articles about 5-Ethyl-5-((1S,2S)-2-hydroxy-1,3,3-trimethyl-4-phenyl-butyl)-5H-dibenzophospholium; iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

ethyl iodide (75-03-6) + (3S,4S)-4-Dibenzophosphol-5-yl-2,2-dimethyl-1-phenyl-pentan-3-ol → 5-Ethyl-5-((1S,2S)-2-hydroxy-1,3,3-trimethyl-4-phenyl-butyl)-5H-dibenzophospholium; iodide (113686-97-8)

Guidance literature:

With aluminium; for 24h; Ambient temperature;

DOI:10.1021/ja00220a036

Reference yield:

2,2-dimethyl-3-phenylpropionaldehyde (1009-62-7) → 5-Ethyl-5-((1S,2S)-2-hydroxy-1,3,3-trimethyl-4-phenyl-butyl)-5H-dibenzophospholium; iodide (113686-97-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 98 percent / tetrahydrofuran / Heating

2: 90 percent / mCPBA / CH₂Cl₂ / 0.33 h / Ambient temperature

3: n-BuLi / tetrahydrofuran / 0.5 h / -50 °C

4: 65 percent / aluminum plug / 24 h / Ambient temperature

With n-butyllithium; 3-chloro-benzenecarboperoxoic acid; aluminium; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja00220a036

Reference yield:

(Z)-4,4-dimethyl-5-phenylpent-2-ene (113460-12-1) → 5-Ethyl-5-((1S,2S)-2-hydroxy-1,3,3-trimethyl-4-phenyl-butyl)-5H-dibenzophospholium; iodide (113686-97-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / mCPBA / CH₂Cl₂ / 0.33 h / Ambient temperature

2: n-BuLi / tetrahydrofuran / 0.5 h / -50 °C

3: 65 percent / aluminum plug / 24 h / Ambient temperature

With n-butyllithium; 3-chloro-benzenecarboperoxoic acid; aluminium; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja00220a036

upstream raw materials:

lithium dibenzophospholyl

ethyl iodide

9-phenyl-9-phosphafluorene

tetraphenylphosphonium bromide

Downstream raw materials:

C₂₇H₃₁OP

C₂₇H₃₁OP

C₂₇H₃₁OP