1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-(4-morpholin-4-ylmethyl-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethylamide

Base Information

Chemical Name:1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-(4-morpholin-4-ylmethyl-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethylamide
CAS No.:1383718-25-9
Molecular Formula:C₃₉H₄₃N₅O₄
Molecular Weight:645.802
Hs Code.:

Synonyms:1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-(4-morpholin-4-ylmethyl-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethylamide

Suppliers and Price of 1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-(4-morpholin-4-ylmethyl-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-(4-morpholin-4-ylmethyl-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-(4-morpholin-4-ylmethyl-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethylamide

There total 17 articles about 1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-(4-morpholin-4-ylmethyl-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1383717-91-6
methyl 1-[2,4-bis(benzyloxy)cumenyl]-5-[p-(morpholin-4-ylmethyl)phenyl]-1H-1,2,3-triazole-4-carboxylate

: 75-04-7,85404-22-4
ethylamine

: 1383718-25-9
1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-(4-morpholin-4-ylmethyl-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethylamide

Guidance literature:: In methanol; at 80 ℃; for 24h; sealed tube;

Reference yield:

: 1383717-81-4
1,5-bis-benzyloxy-2-isopropyl-4-azido-benzene

: 1383718-25-9
1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-(4-morpholin-4-ylmethyl-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethylamide

Guidance literature:: Multi-step reaction with 5 steps

1: chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C

3: triethylamine / dichloromethane / 12.5 h / 0 - 20 °C

4: triethylamine / 12 h / 20 °C

5: methanol / 24 h / 80 °C / sealed tube

With tetrabutyl ammonium fluoride; triethylamine; chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1093190-17-0
tert-butyl[(4-ethynylphenyl)methoxy]dimethylsilane

: 1383718-25-9
1-(2,4-bis-benzyloxy-5-isopropyl-phenyl)-5-(4-morpholin-4-ylmethyl-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethylamide

Guidance literature:: Multi-step reaction with 6 steps

1.1: lithium hexamethyldisilazane / toluene; tetrahydrofuran / 1 h / -78 - -40 °C

1.2: -40 - 20 °C

2.1: chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C

4.1: triethylamine / dichloromethane / 12.5 h / 0 - 20 °C

5.1: triethylamine / 12 h / 20 °C

6.1: methanol / 24 h / 80 °C / sealed tube

With tetrabutyl ammonium fluoride; triethylamine; lithium hexamethyldisilazane; chloro(pentamethylcyclopentadienyl)ruthenium(II) tetramer; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene;