Technology Process of C20H30ClFN2O
There total 5 articles about C20H30ClFN2O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: hydrogenchloride; water / 12 h / Reflux
2: oxalyl dichloride / dichloromethane / 4 h / 20 °C
3: hydrogenchloride; triethylamine / dichloromethane / 8 h / 20 °C
4: borane-THF / tetrahydrofuran / 12 h / Reflux
5: caesium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C
With
hydrogenchloride; borane-THF; oxalyl dichloride; water; caesium carbonate; triethylamine;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.05.030
- Guidance literature:
-
Multi-step reaction with 4 steps
1: oxalyl dichloride / dichloromethane / 4 h / 20 °C
2: hydrogenchloride; triethylamine / dichloromethane / 8 h / 20 °C
3: borane-THF / tetrahydrofuran / 12 h / Reflux
4: caesium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C
With
hydrogenchloride; borane-THF; oxalyl dichloride; caesium carbonate; triethylamine;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.05.030