-4-<<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>amino>-4-oxo-2-butenoic acid

Base Information

• Chemical Name: -4-<<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>amino>-4-oxo-2-butenoic acid
• CAS No.: 120417-14-3
• Molecular Formula: C₁₈H₂₇NO₄Si
• Molecular Weight: 349.502

Synonyms:-4-<<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>amino>-4-oxo-2-butenoic acid

Chemical Property of -4-<<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>amino>-4-oxo-2-butenoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of -4-<<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>amino>-4-oxo-2-butenoic acid

There total 3 articles about -4-<<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>amino>-4-oxo-2-butenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

maleic anhydride (108-31-6) + (S)-2-(tert-butyldimethylsilyloxy)-1-phenylethylamine (120417-13-2) → -4-<<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>amino>-4-oxo-2-butenoic acid (120417-14-3)

Guidance literature:

In diethyl ether; at 0 ℃;

DOI:10.1021/jo00270a008

Reference yield:

(2S)-2-phenylglycinol (20989-17-7) → -4-<<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>amino>-4-oxo-2-butenoic acid (120417-14-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 51 percent / CH₂Cl₂ / Ambient temperature

2: 88 percent / diethyl ether / 0 °C

In diethyl ether; dichloromethane;

DOI:10.1021/jo00270a008

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → -4-<<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>amino>-4-oxo-2-butenoic acid (120417-14-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 51 percent / CH₂Cl₂ / Ambient temperature

2: 88 percent / diethyl ether / 0 °C

In diethyl ether; dichloromethane;

DOI:10.1021/jo00270a008

upstream raw materials:

maleic anhydride

(S)-2-(tert-butyldimethylsilyloxy)-1-phenylethylamine

(2S)-2-phenylglycinol

tert-butyldimethylsilyl chloride

Downstream raw materials:

5-<(S)-2-<<(1,1-Dimethylethyl)dimethylsilyll>oxy>-1-phenylethyl>-3a,6a-dihydro-1-methylpyrrolo<3,4-d>-1,2,3-triazole-4,6(1H,5H)-dione

Acrylic acid (S)-2-(6-methyl-2,4-dioxo-3,6-diaza-bicyclo[3.1.0]hex-3-yl)-2-phenyl-ethyl ester

3-((S)-2-Hydroxy-1-phenyl-ethyl)-6-methyl-3,6-diaza-bicyclo[3.1.0]hexane-2,4-dione

(S)-3-<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>-6-methyl-3,6-diazabicyclo<3.1.0>hexane-2,4-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 120417-14-3 -4-<<2-<<(1,1-Dimethylethyl)dimethylsilyl>oxy>-1-phenylethyl>amino>-4-oxo-2-butenoic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send