120417-13-2Relevant articles and documents
A library of spirooxindoles based on a stereoselective three-component coupling reaction
Lo, Michael M.-C.,Neumann, Christopher S.,Nagayama, Satoshi,Perlstein, Ethan O.,Schreiber, Stuart L.
, p. 16077 - 16086 (2004)
A collection of structurally complex and chemically diverse small molecules is a useful tool to explore cell circuitry. In this article, we report the split-pool synthesis of more than 3000 spirooxindoles on high capacity macrobeads. The key reaction to a
COMPLEMENT MODULATORS AND RELATED METHODS
-
Paragraph 0391, (2020/10/20)
The present disclosure presents compounds and compositions that interact with complement components. Some compounds inhibit complement activity. Included are small molecule compounds and compositions that function as C5 inhibitor compounds. Methods for inhibiting complement activity and methods of treating complement-related indications with the C5 inhibitor compounds and compositions are provided.
FUSED TRIAZOLE AGONISTS OF THE APJ RECEPTOR
-
Paragraph 0291-0292, (2019/05/22)
Compounds of Formula I, pharmaceutically acceptable salts thereof, tautomers thereof, pharmaceutically acceptable salts of the tautomers, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula (I) have the following structure: where the definitions of the variables are provided herein.
