Dabigatran iMpurity J

Base Information

Chemical Name:Dabigatran iMpurity J
CAS No.:211915-00-3
Molecular Formula:C₃₃H₃₉N₇O₅
Molecular Weight:613.717
Hs Code.:
Mol file:211915-00-3.mol

Synonyms:methyl-3-[[[2-[[[4-[amino[[[(hexyloxy)carbonyl]imino]methyl]]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propionate

Suppliers and Price of Dabigatran iMpurity J

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-AlanineMethylEster
25mg
$ 315.00

Total 17 raw suppliers

Chemical Property of Dabigatran iMpurity J

Chemical Property:

Melting Point:>62°C (dec.)
PKA:9.88±0.46(Predicted)
Density:1.25±0.1 g/cm3(Predicted)
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Acetonitrile (Slightly), DMSO (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-AlanineMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-Alanine Methyl Ester was used in preparation of thrombin inhibitors. It was also used to analyze and reduce potential impurities in dabigatra etexilate mesylate processes.

Technology Process of Dabigatran iMpurity J

There total 5 articles about Dabigatran iMpurity J which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 67-56-1
methanol

: 1415506-19-2,212321-78-3
3-[[[2-[[[4-[amino[[[(hexyloxy)carbonyl]amino]methyl]]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propionic acid

: 211915-00-3
methyl-3-[[[2-[[[4-[amino[[[(hexyloxy)carbonyl]imino]methyl]]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propionate

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; N,N-dimethyl-formamide; Temperature; Reagent/catalyst; Solvent; Concentration;