4-(4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine

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Chemical Name:4-(4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine
CAS No.:942921-06-4
Molecular Formula:C₂₃H₂₀BrN₃O₃S
Molecular Weight:498.4
Hs Code.:

Synonyms:4-(4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine

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Chemical Property of 4-(4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine

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Technology Process of 4-(4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine

There total 4 articles about 4-(4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 568577-88-8
4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine

: 889939-26-8
4-bromo-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

: 942921-06-4
4-(4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium hydrogencarbonate; In 1,4-dioxane; at 80 ℃; for 6h;

Reference yield:

: 98-09-9
benzenesulfonyl chloride

: 942921-06-4
4-(4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / dichloromethane / 2 h / 20 °C

2: sodium hydrogencarbonate; bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 6 h / 80 °C

With dmap; bis-triphenylphosphine-palladium(II) chloride; sodium hydrogencarbonate; In 1,4-dioxane; dichloromethane;

Reference yield:

: 1260879-70-6
4-bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine

: 942921-06-4
4-(4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / dichloromethane / 2 h / 20 °C

2: sodium hydrogencarbonate; bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 6 h / 80 °C

With dmap; bis-triphenylphosphine-palladium(II) chloride; sodium hydrogencarbonate; In 1,4-dioxane; dichloromethane;