1H-Benzimidazole-2-carboxaldehyde,1-ethenyl-(9CI)

Base Information

• Chemical Name: 1H-Benzimidazole-2-carboxaldehyde,1-ethenyl-(9CI)
• CAS No.: 118482-08-9
• Molecular Formula: C10H8 N2 O
• Molecular Weight: 172.186
• Mol file: 118482-08-9.mol

Synonyms:1-Ethenyl-1H-Benzimidazole-2-carboxaldehyde;1-Vinyl-1H-benzimidazole-2-carboxaldehyde; 1-Vinylbenzimidazole-2-carboxaldehyde;2-Formyl-1-vinylbenzimidazole

Chemical Property of 1H-Benzimidazole-2-carboxaldehyde,1-ethenyl-(9CI)

Chemical Property:

• PSA: 34.89000
• LogP: 1.94930

Purity/Quality:

1-ethenyl-1H-Benzimidazole-2-carboxaldehyde 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Benzimidazole-2-carboxaldehyde,1-ethenyl-(9CI)

There total 10 articles about 1H-Benzimidazole-2-carboxaldehyde,1-ethenyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(1-vinylbenzimidazol-2-yl)methyleneaminobenzimidazole → 1H-benzimidazol-2-amine (934-32-7) + 1-vinylbenzimidazole-2-carboxaldehyde (118482-08-9)

Guidance literature:

With water; In dimethylsulfoxide-d6; for 120h;

DOI:10.1007/bf02494645

Reference yield:

1-vinylbenzimidazole (26972-40-7) + ethyl acetate-chloroform + formic acid ethyl ester (109-94-4) → 1-vinylbenzimidazole-2-carboxaldehyde (118482-08-9)

Guidance literature:

With n-butyllithium; acetic acid; diisopropylamine; In tetrahydrofuran; hexane; water; ethyl acetate;

Reference yield:

2-(Hydroxymethyl)benzimidazole (4856-97-7) → 1-vinylbenzimidazole-2-carboxaldehyde (118482-08-9)

Guidance literature:

Multi-step reaction with 4 steps

1: acetic acid / 1 h / Heating

2: mercuric acetate, H₂SO₄ / 24 h / Heating

3: KOH / methanol / 0.5 h / Ambient temperature

4: MnO₂ / CH₂Cl₂

With manganese(IV) oxide; potassium hydroxide; sulfuric acid; mercury(II) diacetate; In methanol; dichloromethane; acetic acid;

DOI:10.1016/S0040-4039(01)80360-9

upstream raw materials:

1-vinylbenzimidazole

N,N-dimethyl-formamide

formic acid ethyl ester

1-vinyl-2-hydroxymethylbenzimidazole

Downstream raw materials:

2-[(diphenylphosphinoyl)hydroxymethyl]-1-vinylbenzimidazole