Methyl 2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate

Base Information

Chemical Name:Methyl 2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate
CAS No.:132691-38-4
Molecular Formula:C₁₅H₂₁NO₄
Molecular Weight:279.336
Hs Code.:
DSSTox Substance ID:DTXSID20599522
Wikidata:Q82495417
Mol file:132691-38-4.mol

Synonyms:132691-38-4;methyl 2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate;Methyl 2-(3-(((tert-butoxycarbonyl)amino)methyl)phenyl)acetate;methyl 2-[3-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]acetate;METHYL 2-(3-(N-BOC-AMINOMETHYL)PHENYL)ACETATE;TERT-BUTYL 3-((METHOXYCARBONYL)METHYL) BENZYLCARBAMATE;AB3456;Methyl 2-(3-((tert-butoxycarbonylamino)-methyl)phenyl)acetate;SCHEMBL8786913;DTXSID20599522;AMY17589;MFCD09909447;AKOS025404165;DA-20873;CS-0120431;Methyl 2-(3-[(Boc-amino)methyl]-phenyl)acetate;methyl2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate;Methyl (3-{[(tert-butoxycarbonyl)amino]methyl}phenyl)acetate

Suppliers and Price of Methyl 2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Methyl2-(3-((tert-butoxycarbonylamino)-methyl)phenyl)acetate 97%
1g
$ 720.00

Matrix Scientific
Methyl2-(3-((tert-butoxycarbonylamino)-methyl)phenyl)acetate 97%
500mg
$ 479.00

Crysdot
methyl2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate 95+%
5g
$ 1528.00

Crysdot
methyl2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate 95+%
1g
$ 436.00

Chemenu
methyl2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate 95%
1g
$ 411.00

American Custom Chemicals Corporation
METHYL-2-(3-(N-BOC-AMINOMETHYL)PHENYL)ACETATE 95.00%
5MG
$ 497.67

Total 4 raw suppliers

Chemical Property of Methyl 2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate

Chemical Property:

Boiling Point:400.1±33.0 °C(Predicted)
PKA:12.14±0.46(Predicted)
Density:1.102±0.06 g/cm3(Predicted)
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:279.14705815
Heavy Atom Count:20
Complexity:335

Purity/Quality:

98%min ^*data from raw suppliers

Methyl2-(3-((tert-butoxycarbonylamino)-methyl)phenyl)acetate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC1=CC=CC(=C1)CC(=O)OC

Technology Process of Methyl 2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate

There total 5 articles about Methyl 2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 132691-38-4
methyl 2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate

Guidance literature:

Reference yield:

: 1878-67-7
3-Bromophenylacetic acid

: 132691-38-4
methyl 2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate

Guidance literature:: Multi-step reaction with 4 steps

1: H₂SO₄ / Heating

2: dimethylformamide / Heating

3: H₂; aq. HCl / Pd/C / methanol / 25 °C / 3620.04 Torr

4: Et₃N / tetrahydrofuran / 25 °C

With hydrogenchloride; sulfuric acid; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2005.03.020

Reference yield:

: 52798-00-2
(3-cyano-phenyl)-acetic acid methyl ester

: 132691-38-4
methyl 2-(3-((tert-butoxycarbonylamino)methyl)phenyl)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: H₂; aq. HCl / Pd/C / methanol / 25 °C / 3620.04 Torr

2: Et₃N / tetrahydrofuran / 25 °C

With hydrogenchloride; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2005.03.020