4-benzoyl-8-carbethoxy-10-methyl-4,5a,6,7,9,10a-dodecahydro-Δ^6αΔ^10β-didehydroindolo<3,4-gh>quinoline

Base Information

• Chemical Name: 4-benzoyl-8-carbethoxy-10-methyl-4,5a,6,7,9,10a-dodecahydro-Δ^6αΔ^10β-didehydroindolo<3,4-gh>quinoline
• CAS No.: 1027020-87-6
• Molecular Formula: C₂₅H₂₆N₂O₃
• Molecular Weight: 402.493
• Mol file: 1027020-87-6.mol

Synonyms:4-benzoyl-8-carbethoxy-10-methyl-4,5a,6,7,9,10a-dodecahydro-Δ^6αΔ^10β-didehydroindolo<3,4-gh>quinoline

Chemical Property of 4-benzoyl-8-carbethoxy-10-methyl-4,5a,6,7,9,10a-dodecahydro-Δ^6αΔ^10β-didehydroindolo<3,4-gh>quinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-benzoyl-8-carbethoxy-10-methyl-4,5a,6,7,9,10a-dodecahydro-Δ^6αΔ^10β-didehydroindolo<3,4-gh>quinoline

There total 1 articles about 4-benzoyl-8-carbethoxy-10-methyl-4,5a,6,7,9,10a-dodecahydro-Δ^6αΔ^10β-didehydroindolo<3,4-gh>quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Bromo-2-bromomethyl-propionic acid ethyl ester (58539-11-0) + Phenyl-(5-pyrrolidin-1-yl-2a,3-dihydro-2H-benzo[cd]indol-1-yl)-methanone + methylamine (74-89-5) → 4-benzoyl-8-carbethoxy-10-methyl-4,5a,6,7,9,10a-dodecahydro-Δ6αΔ10β-didehydroindolo<3,4-gh>quinoline (1027020-87-6)

Guidance literature:

With triethylamine; multistep reaction; mechanism;

DOI:10.1002/jhet.5570320435

Reference yield: 98.0%

4-benzoyl-8-carbethoxy-10-methyl-4,5a,6,7,9,10a-dodecahydro-Δ6αΔ10β-didehydroindolo<3,4-gh>quinoline (1027020-87-6) → 4-benzoyl-8-carbethoxy-10-methyl-4,5a,6,7,9,10a-dodecahydro-Δ10β-dehydroindolo<3,4-gh>quinoline (858355-21-2)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In tetrahydrofuran; for 2h; Ambient temperature;

DOI:10.1002/jhet.5570320435

upstream raw materials:

3-Bromo-2-bromomethyl-propionic acid ethyl ester

methylamine

Downstream raw materials:

4-benzoyl-8-carbethoxy-10-methyl-4,5a,6,7,9,10a-dodecahydro-Δ^10β-dehydroindolo<3,4-gh>quinoline