5-[Chloro(difluoro)methyl]-1,2-oxazole

Base Information

Chemical Name:5-[Chloro(difluoro)methyl]-1,2-oxazole
CAS No.:116611-76-8
Molecular Formula:C₄H₂ClF₂NO
Molecular Weight:153.516
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10557090
Wikidata:Q82438853
Mol file:116611-76-8.mol

Synonyms:116611-76-8;5-(chlorodifluoromethyl)-1,2-oxazole;5-[Chloro(difluoro)methyl]-1,2-oxazole;5-(Chloro-difluoro-methyl)-isoxazole;5-(chlorodifluoromethyl)isoxazole;Isoxazole, 5-(chlorodifluoromethyl)-;5-[chloro(difluoro)methyl]isoxazole;DL-ALPHA-LIPOICACID;SCHEMBL9814076;DTXSID10557090;MFCD04972715;AKOS006343722;5-[chloranyl-bis(fluoranyl)methyl]-1,2-oxazole;A803650

Suppliers and Price of 5-[Chloro(difluoro)methyl]-1,2-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

CHESS?
SG000387:5-(Chloro-difluoro-methyl)-isoxazole 96
5 g
$ 1140.00

American Custom Chemicals Corporation
5-(CHLORO-DIFLUORO-METHYL)-ISOXAZOLE 95.00%
1G
$ 642.99

Total 11 raw suppliers

Chemical Property of 5-[Chloro(difluoro)methyl]-1,2-oxazole

Chemical Property:

Vapor Pressure:3.18mmHg at 25°C
Refractive Index:1.415
Boiling Point:159.9°Cat760mmHg
Flash Point:50.5°C
PSA：26.03000
Density:1.463g/cm³
LogP:1.96270
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:152.9792977
Heavy Atom Count:9
Complexity:111

Purity/Quality:

97% ^*data from raw suppliers

SG000387:5-(Chloro-difluoro-methyl)-isoxazole 96 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,F
Statements: 11-41
Safety Statements: 16-26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(ON=C1)C(F)(F)Cl

Technology Process of 5-[Chloro(difluoro)methyl]-1,2-oxazole

There total 1 articles about 5-[Chloro(difluoro)methyl]-1,2-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.5%

: 88283-10-7
5-trichloromethyl isoxazole

: 116611-76-8
5-chlorodifluoromethyl isoxazole

Guidance literature:: With hydrogen fluoride; antimonypentachloride; autoclave, -5 deg C to 0 deg C, 1 h then 18 bar, to 150 deg C during 3 h, 1 h;
DOI:10.1016/S0022-1139(00)80124-4