{5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3-isopropyl-2-methoxymethoxyphenyl}boronic acid

Base Information

• Chemical Name: {5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3-isopropyl-2-methoxymethoxyphenyl}boronic acid
• CAS No.: 417871-20-6
• Molecular Formula: C₂₉H₄₇BO₅Si
• Molecular Weight: 514.586
• Mol file: 417871-20-6.mol

Synonyms:{5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3-isopropyl-2-methoxymethoxyphenyl}boronic acid

Chemical Property of {5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3-isopropyl-2-methoxymethoxyphenyl}boronic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3-isopropyl-2-methoxymethoxyphenyl}boronic acid

There total 1 articles about {5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3-isopropyl-2-methoxymethoxyphenyl}boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Triisopropyl borate (5419-55-6) + 3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)-O-triisopropylsilylphenol (328236-46-0) → {5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3-isopropyl-2-methoxymethoxyphenyl}boronic acid (417871-20-6)

Guidance literature:

3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)-O-triisopropylsilylphenol; With n-butyllithium; In tetrahydrofuran; hexane; at 20 ℃; for 2h;

Triisopropyl borate; In tetrahydrofuran; hexane; at 20 ℃; for 1h;

DOI:10.1016/S0968-0896(01)00284-X

Reference yield: 75.0%

o-nitroiodobenzene (609-73-4) + {5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3-isopropyl-2-methoxymethoxyphenyl}boronic acid (417871-20-6) → triisopropyl-[4-(5-isopropyl-6-methoxymethoxy-2'-nitrobiphenyl-3-ylmethyl)-3,5-dimethylphenoxy]silane (417871-36-4)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; caesium carbonate; In ethanol; toluene; for 8h; Heating;

DOI:10.1016/S0968-0896(01)00284-X

Reference yield: 71.0%

4-iodobenzoic acid (619-58-9) + {5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3-isopropyl-2-methoxymethoxyphenyl}boronic acid (417871-20-6) → 5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3'-isopropyl-2'-methoxymethoxybiphenyl-4-carboxylic acid (417871-40-0)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; caesium carbonate; In ethanol; toluene; for 8h; Heating;

DOI:10.1016/S0968-0896(01)00284-X

upstream raw materials:

Triisopropyl borate

3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)-O-triisopropylsilylphenol

Downstream raw materials:

triisopropyl-[4-(5-isopropyl-6-methoxymethoxy-4'-nitrobiphenyl-3-ylmethyl)-3,5-dimethylphenoxy]silane

triisopropyl-[4-(5-isopropyl-6-methoxymethoxybiphenyl-3-ylmethyl)-3,5-dimethylphenoxy]silane

triisopropyl-[4-(5-isopropyl-6-methoxymethoxy-3'-nitrobiphenyl-3-ylmethyl)-3,5-dimethylphenoxy]silane

5'-[2,6-dimethyl-4-(triisopropylsilanyloxy)benzyl]-3'-isopropyl-2'-methoxymethoxybiphenyl-4-carboxylic acid amide