7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Base Information

Chemical Name:7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane
CAS No.:226936-47-6
Molecular Formula:C₅₀H₅₈N₆O₁₂
Molecular Weight:935.044
Hs Code.:

Synonyms:7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Suppliers and Price of 7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

There total 7 articles about 7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 51304-73-5
dimethyl 5-hydrazinylisophthalate

: 226936-40-9
7,16-bis<4-(1-oxo-2-propenyl)phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

: 226936-47-6
7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Guidance literature:: In acetic acid; for 264h; Ambient temperature; further reagent and conditions;
DOI:10.1016/S0040-4020(99)00167-2

Reference yield:

: 456-03-1
1-(4-fluorophenyl)propan-1-one

: 226936-47-6
7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Guidance literature:: Multi-step reaction with 4 steps

1: 28 percent / tetrabutylammonium fluoride trihydrate / 12 h / 150 °C

2: 1.) LDA / 1) THF, heptane, -78 deg C, 1 h; 2) THF, heptane, 0 deg C, 2 h

3: 75 percent / NaHCO₃, NaIO₄ / tetrahydrofuran; methanol; H₂O / 0.5 h / Ambient temperature

4: 52 percent / acetic acid / 264 h / Ambient temperature; further reagent and conditions

With sodium periodate; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; lithium diisopropyl amide; In tetrahydrofuran; methanol; water; acetic acid;
DOI:10.1016/S0040-4020(99)00167-2

Reference yield:

: 99-31-0
5-aminoisophthalic acid

: 226936-47-6
7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) sodium nitrite, aq. HCl, 2.) sodium sulphite, 3.) conc. HCl / 1) water, 0-5 deg C, 1 h; 2) water, 50-60 deg C, 45 min; 3) water, 90 deg C, 1 hi930

2: H₂SO₄ / 2 h / Heating

3: 52 percent / acetic acid / 264 h / Ambient temperature; further reagent and conditions

With hydrogenchloride; sulfuric acid; sodium sulfite; sodium nitrite; In acetic acid;
DOI:10.1016/S0040-4020(99)00167-2