dimethyl 5-hydrazinylisophthalate

Base Information

• Chemical Name: dimethyl 5-hydrazinylisophthalate
• CAS No.: 51304-73-5
• Molecular Formula: C₁₀H₁₂N₂O₄
• Molecular Weight: 224.216
• Mol file: 51304-73-5.mol

Synonyms:dimethyl 5-hydrazinylisophthalate

Chemical Property of dimethyl 5-hydrazinylisophthalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl 5-hydrazinylisophthalate

There total 3 articles about dimethyl 5-hydrazinylisophthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

dimethyl 5-aminoisophthalate (99-27-4) → dimethyl 5-hydrazinylisophthalate (51304-73-5)

Guidance literature:

dimethyl 5-aminoisophthalate; With hydrogenchloride; sodium nitrite; In ethanol; water; Cooling;

With tin(II) chloride dihdyrate; In ethanol; water; at 20 ℃; for 2h;

DOI:10.1021/acs.inorgchem.9b00696

Reference yield:

5-aminoisophthalic acid (99-31-0) → dimethyl 5-hydrazinylisophthalate (51304-73-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) sodium nitrite, aq. HCl, 2.) sodium sulphite, 3.) conc. HCl / 1) water, 0-5 deg C, 1 h; 2) water, 50-60 deg C, 45 min; 3) water, 90 deg C, 1 hi930

2: H₂SO₄ / 2 h / Heating

With hydrogenchloride; sulfuric acid; sodium sulfite; sodium nitrite;

DOI:10.1016/S0040-4020(99)00167-2

Reference yield:

methanol (67-56-1) + 5-hydrazinyl-1,3-benzene dicarboxylic acid (121385-69-1) → dimethyl 5-hydrazinylisophthalate (51304-73-5)

Guidance literature:

With sulfuric acid; for 2h; Heating;

DOI:10.1016/S0040-4020(99)00167-2

upstream raw materials:

methanol

5-hydrazinyl-1,3-benzene dicarboxylic acid

5-aminoisophthalic acid

dimethyl 5-aminoisophthalate

Downstream raw materials:

dimethyl 5-<3-(2,3,5,6,8,9,11,12,14,15-decahydro-1,4,7,10,13,16-benzohexaoxacyclooctadecin-18-yl)-4,5-dihydro-1H-pyrazol-1-yl>isophthalate

7,13-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10-trioxa-7,13-diazacyclopentadecane

7,16-bis<4-<1-(3,5-dimethoxycarbonyl)phenyl-4,5-dihydro-1H-pyrazol-3-yl>phenyl>-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane