3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde

Base Information

• Chemical Name: 3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde
• CAS No.: 1361455-25-5
• Molecular Formula: C₁₆H₂₁NO₄
• Molecular Weight: 291.347
• Mol file: 1361455-25-5.mol

Synonyms:3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde

Chemical Property of 3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde

There total 1 articles about 3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydropyridine (113225-07-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde (1361455-25-5)

Guidance literature:

1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydropyridine; N,N-dimethyl-formamide; With trichlorophosphate; at 0 - 25 ℃; for 2.5h;

With water; sodium carbonate; Cooling with ice;

DOI:10.3109/14756366.2011.587416

Reference yield: 94.0%

N-(3-acetylphenyl)-4-chlorobenzamide + 3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde (1361455-25-5) → C31H31ClN2O5

Guidance literature:

N-(3-acetylphenyl)-4-chlorobenzamide; With sodium hydroxide; In ethanol; for 0.0833333h;

3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde; In ethanol; at 20 ℃; for 24h;

DOI:10.3109/14756366.2011.587416

Reference yield: 93.0%

N-(3-acetylphenyl)-4-methoxybenzamide (316150-74-0) + 3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde (1361455-25-5) → C32H34N2O6

Guidance literature:

N-(3-acetylphenyl)-4-methoxybenzamide; With sodium hydroxide; In ethanol; for 0.0833333h;

3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxybenzaldehyde; In ethanol; at 20 ℃; for 24h;

DOI:10.3109/14756366.2011.587416

upstream raw materials:

1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydropyridine

N,N-dimethyl-formamide

Downstream raw materials:

2-fluoro-N-(3-((2E)-3-(3-(1,2,3,6-tetrahydro-1-methylpyridin-4-yl)-2,4,6-trimethoxyphenyl)acryloyl)phenyl)benzamide