Technology Process of 3-(3,4,5-trihydroxyphenyl)propyl β-D-glucopyranoside
There total 12 articles about 3-(3,4,5-trihydroxyphenyl)propyl β-D-glucopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
methanol; ethyl acetate;
for 5h;
under 2585.81 Torr;
Inert atmosphere;
DOI:10.1021/jm401311d
- Guidance literature:
-
With
5%-palladium/activated carbon; hydrogen;
In
methanol;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: thionyl chloride / dichloromethane
2.1: potassium carbonate / dimethyl sulfoxide / 6 h / 50 °C
3.1: sodium chloride / dimethyl sulfoxide / 5 h / Reflux
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 2.5 h / 20 °C / Reflux
5.1: silver carbonate / diethyl ether; dichloromethane / 1 h / 20 °C / Inert atmosphere; Molecular sieve
5.2: 14 h / 20 °C / Inert atmosphere; Darkness
6.1: sodium methylate / methanol / 2 h / 20 °C
7.1: 5%-palladium/activated carbon; hydrogen / methanol / 20 °C
With
lithium aluminium tetrahydride; thionyl chloride; 5%-palladium/activated carbon; hydrogen; sodium methylate; potassium carbonate; silver carbonate; sodium chloride;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; dimethyl sulfoxide;
5.1: |Koenigs-Knorr Glycosidation / 5.2: |Koenigs-Knorr Glycosidation;
