3-hydroxy-3-[4-(6-methoxynaphthalen-2-ylamino)phenyl]-2,2-dimethylpropionic acid methyl ester

Base Information

Chemical Name:3-hydroxy-3-[4-(6-methoxynaphthalen-2-ylamino)phenyl]-2,2-dimethylpropionic acid methyl ester
CAS No.:1202273-92-4
Molecular Formula:C₂₃H₂₅NO₄
Molecular Weight:379.456
Hs Code.:

Synonyms:3-hydroxy-3-[4-(6-methoxynaphthalen-2-ylamino)phenyl]-2,2-dimethylpropionic acid methyl ester

Suppliers and Price of 3-hydroxy-3-[4-(6-methoxynaphthalen-2-ylamino)phenyl]-2,2-dimethylpropionic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-hydroxy-3-[4-(6-methoxynaphthalen-2-ylamino)phenyl]-2,2-dimethylpropionic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-hydroxy-3-[4-(6-methoxynaphthalen-2-ylamino)phenyl]-2,2-dimethylpropionic acid methyl ester

There total 3 articles about 3-hydroxy-3-[4-(6-methoxynaphthalen-2-ylamino)phenyl]-2,2-dimethylpropionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1202273-87-7
3-(4-aminophenyl)-3-hydroxy-2,2-dimethylpropionic acid methyl ester

: 156641-98-4
(6-methoxy-2-naphthalene)boronic acid

: 1202273-92-4
3-hydroxy-3-[4-(6-methoxynaphthalen-2-ylamino)phenyl]-2,2-dimethylpropionic acid methyl ester

Guidance literature:: With pyridine; copper diacetate; In dichloromethane; at 20 ℃; for 48h; Molecular sieve; Air;
DOI:10.1021/jm101583w

Reference yield:

: methyl 3-hydroxy-2,2-dimethyl-3-(4-nitrophenyl)propionate

: 1202273-92-4
3-hydroxy-3-[4-(6-methoxynaphthalen-2-ylamino)phenyl]-2,2-dimethylpropionic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: palladium on carbon; hydrogen / ethanol / 0.5 h

2: pyridine; copper diacetate / dichloromethane / 48 h / 20 °C / Molecular sieve; Air

With pyridine; palladium on carbon; hydrogen; copper diacetate; In ethanol; dichloromethane; 2: Suzuki coupling;
DOI:10.1021/jm101583w

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 1202273-92-4
3-hydroxy-3-[4-(6-methoxynaphthalen-2-ylamino)phenyl]-2,2-dimethylpropionic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine N-oxide; lithium chloride / N,N-dimethyl-formamide / 18 h

2: palladium on carbon; hydrogen / ethanol / 0.5 h

3: pyridine; copper diacetate / dichloromethane / 48 h / 20 °C / Molecular sieve; Air

With pyridine; pyridine N-oxide; palladium on carbon; hydrogen; copper diacetate; lithium chloride; In ethanol; dichloromethane; N,N-dimethyl-formamide; 1: Mukaiyama aldol condensation / 3: Suzuki coupling;
DOI:10.1021/jm101583w