4-(2-methyl-1H-benzimidazol-1-yl)butanoic acid

Base Information

Chemical Name:4-(2-methyl-1H-benzimidazol-1-yl)butanoic acid
CAS No.:115444-73-0
Molecular Formula:C₁₂H₁₄N₂O₂
Molecular Weight:218.255
Hs Code.:2933290090
DSSTox Substance ID:DTXSID60402622
Wikidata:Q82206049
Mol file:115444-73-0.mol

Synonyms:115444-73-0;4-(2-methyl-1H-benzimidazol-1-yl)butanoic acid;4-(2-methylbenzimidazol-1-yl)butanoic acid;4-(2-Methyl-benzoimidazol-1-yl)-butyric acid;4-(2-methyl-1H-1,3-benzodiazol-1-yl)butanoic acid;MFCD00879013;1H-Benzimidazole-1-butanoic acid, 2-methyl-;4-(2-Methyl-1H-benzo[d]imidazol-1-yl)butanoic acid;DTXSID60402622;BBL029081;STK918975;AKOS000163436;VS-09098;4-(2-methyl-1-benzimidazolyl)butanoic acid;CS-0312909;FT-0642808;A803436;AQ-086/43383938;4-(2-Methyl-1H-benzimidazol-1-yl)butanoic acid, AldrichCPR

Suppliers and Price of 4-(2-methyl-1H-benzimidazol-1-yl)butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2-Methyl-1H-benzimidazol-1-yl)butanoicAcid
500mg
$ 155.00

Matrix Scientific
4-(2-Methyl-benzoimidazol-1-yl)-butyric acid
1g
$ 378.00

Crysdot
4-(2-Methyl-1H-benzo[d]imidazol-1-yl)butanoicacid 97%
5g
$ 701.00

American Custom Chemicals Corporation
4-(2-METHYL-1H-BENZIMIDAZOL-1-YL)BUTANOIC ACID 95.00%
500MG
$ 777.32

AHH
4-(2-Methyl-1H-benzimidazol-1-yl)butanoicacid 90%
10g
$ 488.00

AccelPharmtech
2-methyl-1H-Benzimidazole-1-butanoicacid 97.00%
25G
$ 4320.00

AccelPharmtech
2-methyl-1H-Benzimidazole-1-butanoicacid 97.00%
5G
$ 2330.00

AccelPharmtech
2-methyl-1H-Benzimidazole-1-butanoicacid 97.00%
1G
$ 2070.00

Total 8 raw suppliers

Chemical Property of 4-(2-methyl-1H-benzimidazol-1-yl)butanoic acid

Chemical Property:

Vapor Pressure:3.05E-09mmHg at 25°C
Melting Point:234 °C
Refractive Index:1.604
Boiling Point:459.6°Cat760mmHg
PKA:4.60±0.10(Predicted)
Flash Point:231.8°C
PSA：55.12000
Density:1.22g/cm³
LogP:2.20950
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:218.105527694
Heavy Atom Count:16
Complexity:257

Purity/Quality:

97% ^*data from raw suppliers

4-(2-Methyl-1H-benzimidazol-1-yl)butanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=CC=CC=C2N1CCCC(=O)O

Technology Process of 4-(2-methyl-1H-benzimidazol-1-yl)butanoic acid

There total 3 articles about 4-(2-methyl-1H-benzimidazol-1-yl)butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.5%

: 115444-75-2
methyl 2-(2-methyl-1H-benzimidazol-1-yl)acetate

: 115444-73-0
1-(3-carboxypropyl)-2-methylbenzimidazole

Guidance literature:: With sodium hydroxide; In ethanol; for 0.5h; Ambient temperature;
DOI:10.1248/cpb.38.301

Reference yield:

: 615-15-6
2-Methyl-1H-benzimidazole

: 115444-73-0
1-(3-carboxypropyl)-2-methylbenzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) THF, 0 deg C 2.) 2h r. t.

2: 82.5 percent / NaOH / ethanol / 0.5 h / Ambient temperature

With sodium hydroxide; sodium hydride; In ethanol;
DOI:10.1248/cpb.38.301