ACETIC ACID 1-OXY-PYRIDIN-3-YLMETHYL ESTER

Base Information

• Chemical Name: ACETIC ACID 1-OXY-PYRIDIN-3-YLMETHYL ESTER
• CAS No.: 114951-34-7
• Molecular Formula: C8H9 N O3
• Molecular Weight: 165.14608
• Mol file: 114951-34-7.mol

Synonyms:3-Pyridinemethanol,acetate (ester), 1-oxide (9CI); 3-(Acetoxymethyl)pyridine 1-oxide

Chemical Property of ACETIC ACID 1-OXY-PYRIDIN-3-YLMETHYL ESTER

Chemical Property:

• PSA: 51.76000
• LogP: 1.17820

Purity/Quality:

99% ^*data from raw suppliers

ACETIC ACID 1-OXY-PYRIDIN-3-YLMETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ACETIC ACID 1-OXY-PYRIDIN-3-YLMETHYL ESTER

There total 3 articles about ACETIC ACID 1-OXY-PYRIDIN-3-YLMETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-pyridylcarbinol-N-oxide (6968-72-5) + acetic anhydride (108-24-7) → 3-Acetoxymethylpyridine-N-oxide (114951-34-7)

Guidance literature:

In chloroform; Ambient temperature;

Reference yield: 80.0%

3-(acetoxymethyl)pyridine (10072-09-0) → 3-Acetoxymethylpyridine-N-oxide (114951-34-7)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; for 2h; Ambient temperature;

Reference yield:

3-hydroxymethylpyridin (100-55-0) → 3-Acetoxymethylpyridine-N-oxide (114951-34-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 6.1 g / 1.5 h / 60 °C

2: 80 percent / m-chloroperbenzoic acid (m-CPBA) / CHCl₃ / 2 h / Ambient temperature

With 3-chloro-benzenecarboperoxoic acid; In chloroform;

upstream raw materials:

3-pyridylcarbinol-N-oxide

acetic anhydride

3-(acetoxymethyl)pyridine

3-hydroxymethylpyridin

Downstream raw materials:

3-Acetoxymethyl-6-cyanopyridine

3-Acetoxymethyl-2-cynaopyridine

5-(hydroxymethyl)pyridine-2-carbonitrile

2-cyanopyridine-5-carboxyaldehyde

Refernces