N,N,3,4-Tetramethylpiperazine-1-carboxamide

Base Information

Chemical Name:N,N,3,4-Tetramethylpiperazine-1-carboxamide
CAS No.:114649-88-6
Molecular Formula:C₉H₁₉N₃O
Molecular Weight:185.269
Hs Code.:
DSSTox Substance ID:DTXSID70555734
Mol file:114649-88-6.mol

Synonyms:114649-88-6;N,N,3,4-TETRAMETHYLPIPERAZINE-1-CARBOXAMIDE;1-Piperazinecarboxamide,N,N,3,4-tetramethyl-(9CI);SCHEMBL24127263;DTXSID70555734

Suppliers and Price of N,N,3,4-Tetramethylpiperazine-1-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of N,N,3,4-Tetramethylpiperazine-1-carboxamide

Chemical Property:

PSA：26.79000
LogP:0.17970
XLogP3:0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:185.152812238
Heavy Atom Count:13
Complexity:193

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CN(CCN1C)C(=O)N(C)C

Technology Process of N,N,3,4-Tetramethylpiperazine-1-carboxamide

There total 5 articles about N,N,3,4-Tetramethylpiperazine-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 114649-92-2
3-Methyl-piperazine-1-carboxylic acid dimethylamide

: 74-88-4
methyl iodide

: 114649-88-6
1,2-dimethyl-4-(N,N-dimethylcarbamoyl) piperazine

Guidance literature:: With triethylamine; In acetone; for 48h; Ambient temperature;

Reference yield:

: 23936-11-0
3-methylpiperazin-2-one

: 114649-88-6
1,2-dimethyl-4-(N,N-dimethylcarbamoyl) piperazine

Guidance literature:: Multi-step reaction with 5 steps

1: 60 percent / methanol / 24 h / Heating

2: 70 percent / lithium aluminium hydride / tetrahydrofuran / 72 h / Heating

3: 60 percent / triethylamine / benzene / Heating

4: 68 percent / hydrogen / 10percent Pd-C / acetic acid / 1838.8 Torr

5: 68 percent / triethylamine / acetone / 48 h / Ambient temperature

With lithium aluminium tetrahydride; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; acetic acid; acetone; benzene;

Reference yield:

: 114649-90-0
4-Benzyl-3-methyl-piperazine-1-carboxylic acid dimethylamide

: 114649-88-6
1,2-dimethyl-4-(N,N-dimethylcarbamoyl) piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / hydrogen / 10percent Pd-C / acetic acid / 1838.8 Torr

2: 68 percent / triethylamine / acetone / 48 h / Ambient temperature

With hydrogen; triethylamine; palladium on activated charcoal; In acetic acid; acetone;