Methyl 2-amino-1H-indole-3-carboxylate

Base Information

Chemical Name:Methyl 2-amino-1H-indole-3-carboxylate
CAS No.:113772-14-8
Molecular Formula:C10H10 N2 O2
Molecular Weight:190.2
Hs Code.:
DSSTox Substance ID:DTXSID40569227
Wikidata:Q82456332
Mol file:113772-14-8.mol

Synonyms:113772-14-8;Methyl 2-amino-1H-indole-3-carboxylate;METHYL 2-AMINOINDOLE-3-CARBOXYLATE;Methyl 2-aminoindole-3-carboxylateSee E898525;Methyl 2-aminoindole-3-carboxylate See E898525;SCHEMBL1807094;DTXSID40569227;XPOFELVXMSSKQL-UHFFFAOYSA-N;AKOS006272698;Methyl2-amino-1H-indole-3-carboxylate;CS-0301877;E88045;EN300-2689011;1h-indole-3-carboxylic acid,2-amino-,methyl ester;J-003021

Suppliers and Price of Methyl 2-amino-1H-indole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl2-aminoindole-3-carboxylate
10g
$ 1100.00

American Custom Chemicals Corporation
METHYL-2-AMINOINDOLE-3-CARBOXYLATE 95.00%
5MG
$ 500.52

Total 5 raw suppliers

Chemical Property of Methyl 2-amino-1H-indole-3-carboxylate

Chemical Property:

Vapor Pressure:2.13E-06mmHg at 25°C
Refractive Index:1.694
Boiling Point:393.4°C at 760 mmHg
Flash Point:191.7°C
PSA：68.11000
Density:1.339g/cm³
LogP:2.11790
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:190.074227566
Heavy Atom Count:14
Complexity:232

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-aminoindole-3-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(NC2=CC=CC=C21)N
Uses Methyl 2-aminoindole-3-carboxylate (cas# 113772-14-8) is a compound useful in organic synthesis.

Technology Process of Methyl 2-amino-1H-indole-3-carboxylate

There total 5 articles about Methyl 2-amino-1H-indole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: methyl 1-(pyridin-2-carbonyl)indole-3-carboxylate

: 113772-14-8
methyl 2-amino-1H-indole-3-carboxylate

Guidance literature:: methyl 1-(pyridin-2-carbonyl)indole-3-carboxylate; With tert.-butylnitrite; copper diacetate; In 1,4-dioxane; at 70 ℃; for 12h;

With hydrazine hydrate; FeCl₃/C; In 1,4-dioxane; ethanol; at 70 ℃;

Reference yield: 73.0%

: 143321-89-5
2,2,2-trifluoro-N-(2-iodophenyl)acetamide

: 105-34-0
methyl 2-cyanoacetate

: 113772-14-8
methyl 2-amino-1H-indole-3-carboxylate

Guidance literature:: 2,2,2-trifluoro-N-(2-iodophenyl)acetamide; methyl 2-cyanoacetate; With potassium carbonate; L-proline; In dimethyl sulfoxide; for 0.25h; Inert atmosphere;

With copper(l) iodide; In dimethyl sulfoxide; at 60 ℃; for 12h; Inert atmosphere;
DOI:10.1002/adsc.200900887

Reference yield: 71.0%

: 2727-71-1
N-(2-bromophenyl)-2,2,2-trifluoroacetamide

: 105-34-0
methyl 2-cyanoacetate

: 113772-14-8
methyl 2-amino-1H-indole-3-carboxylate

Guidance literature:: N-(2-bromophenyl)-2,2,2-trifluoroacetamide; methyl 2-cyanoacetate; With potassium carbonate; L-proline; In dimethyl sulfoxide; for 0.25h; Inert atmosphere;

With copper(l) iodide; In dimethyl sulfoxide; at 60 ℃; for 12h; Inert atmosphere;
DOI:10.1002/adsc.200900887