4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide

Base Information

• Chemical Name: 4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide
• CAS No.: 344361-86-0
• Molecular Formula: C₅H₁₁N₃S*HI
• Molecular Weight: 273.141
• Mol file: 344361-86-0.mol

Synonyms:4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide

Chemical Property of 4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide

There total 1 articles about 4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N′-carbamothioyl-N,N-dimethylformimidamide (83490-20-4) + methyl iodide (74-88-4) → 4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide (344361-86-0)

Guidance literature:

In tetrahydrofuran;

DOI:10.1016/j.tet.2010.10.059

Reference yield: 92.0%

2,3,5-tri-O-benzoyl-β-D-ribofuranosyl isothiocyanate (58214-53-2) + 4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide (344361-86-0) → 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-4-methylsulfanyl-1,3,5-triazine-2(1H)-thione (77049-72-0)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; regioselective reaction;

DOI:10.1055/s-0028-1083156

Reference yield: 80.0%

4-(dimethylamino)-2-methylsulfanyl-1,3-diazabuta-1,3-dienium iodide (344361-86-0) + phenylacetyl chloride (103-80-0) → 2-thiomethyl-5-phenyl-6-pyrimidone (61044-90-4)

Guidance literature:

With triethylamine; In dichloromethane;

DOI:10.1016/j.tet.2010.10.059

upstream raw materials:

N′-carbamothioyl-N,N-dimethylformimidamide

methyl iodide

Downstream raw materials:

1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-4-methylsulfanyl-1,3,5-triazine-2(1H)-thione

2-Methylthiouracil

2-thiomethyl-5-phenyl-6-pyrimidone