4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-nitro-benzoic acid methyl ester

Base Information

Chemical Name:4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-nitro-benzoic acid methyl ester
CAS No.:217462-54-9
Molecular Formula:C₂₅H₂₇NO₅Si
Molecular Weight:449.579
Hs Code.:

Synonyms:4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-nitro-benzoic acid methyl ester

Suppliers and Price of 4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-nitro-benzoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-nitro-benzoic acid methyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-nitro-benzoic acid methyl ester

There total 4 articles about 4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-nitro-benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 89950-93-6
methyl 4-(hydroxymethyl)-3-nitrobenzoate

: 58479-61-1
tert-butylchlorodiphenylsilane

: 217462-54-9
4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-nitro-benzoic acid methyl ester

Guidance literature:: With dmap; triethylamine; In dichloromethane; for 2h; Ambient temperature;
DOI:10.1055/s-1998-1900

Reference yield:

: 6232-88-8
4-bromomethylbenzoic Acid

: 217462-54-9
4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-nitro-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / HNO₃, H₂O / 3 h / -10 °C

2: 91 percent / Na₂CO₃, H₂O / acetone / 12 h / Heating

3: 83 percent / BF₃*OEt₂ / 15 h / Heating

4: 95 percent / DMAP, Et₃N / CH₂Cl₂ / 2 h / Ambient temperature

With dmap; boron trifluoride diethyl etherate; water; nitric acid; sodium carbonate; triethylamine; In dichloromethane; acetone;
DOI:10.1055/s-1998-1900

Reference yield:

: 55715-03-2
4-bromomethyl-3-nitrobenzoic acid

: 217462-54-9
4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-nitro-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / Na₂CO₃, H₂O / acetone / 12 h / Heating

2: 83 percent / BF₃*OEt₂ / 15 h / Heating

3: 95 percent / DMAP, Et₃N / CH₂Cl₂ / 2 h / Ambient temperature

With dmap; boron trifluoride diethyl etherate; water; sodium carbonate; triethylamine; In dichloromethane; acetone;
DOI:10.1055/s-1998-1900