2-((naphthalen-2-yloxy)methyl)-5-((2,4,5-triphenyl-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

Base Information

Chemical Name:2-((naphthalen-2-yloxy)methyl)-5-((2,4,5-triphenyl-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole
CAS No.:1338334-77-2
Molecular Formula:C₃₅H₂₆N₄O₂
Molecular Weight:534.617
Hs Code.:

Synonyms:2-((naphthalen-2-yloxy)methyl)-5-((2,4,5-triphenyl-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

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Chemical Property of 2-((naphthalen-2-yloxy)methyl)-5-((2,4,5-triphenyl-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

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Technology Process of 2-((naphthalen-2-yloxy)methyl)-5-((2,4,5-triphenyl-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

There total 5 articles about 2-((naphthalen-2-yloxy)methyl)-5-((2,4,5-triphenyl-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 120-23-0
(2-naphthoyl)oxyacetic acid

: 255065-87-3
2‐(2,4,5‐triphenyl‐1H‐imidazol‐1‐yl)acetohydrazide

: 1338334-77-2
2-((naphthalen-2-yloxy)methyl)-5-((2,4,5-triphenyl-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

Guidance literature:: With trichlorophosphate; for 0.166667h; Microwave irradiation;
DOI:10.2174/157018011794578196

Reference yield:

: 134-81-6
benzil

: 1338334-77-2
2-((naphthalen-2-yloxy)methyl)-5-((2,4,5-triphenyl-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid; ammonium acetate / ethanol / Reflux

2.1: potassium carbonate / N,N-dimethyl-formamide / 52 h / 75 - 80 °C

3.1: ethanol / 0.33 h / 20 °C

3.2: 3 h / Reflux

4.1: trichlorophosphate / 0.17 h / Microwave irradiation

With ammonium acetate; potassium carbonate; acetic acid; trichlorophosphate; In ethanol; N,N-dimethyl-formamide;
DOI:10.2174/157018011794578196

Reference yield:

: 484-47-9
lophine

: 1338334-77-2
2-((naphthalen-2-yloxy)methyl)-5-((2,4,5-triphenyl-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 52 h / 75 - 80 °C

2.1: ethanol / 0.33 h / 20 °C

2.2: 3 h / Reflux

3.1: trichlorophosphate / 0.17 h / Microwave irradiation

With potassium carbonate; trichlorophosphate; In ethanol; N,N-dimethyl-formamide;
DOI:10.2174/157018011794578196