1-(4'-METHYL)-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE

Base Information

Chemical Name:1-(4'-METHYL)-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE
CAS No.:112891-31-3
Molecular Formula:C16H17 N
Molecular Weight:223.318
Hs Code.:2933499090
Mol file:112891-31-3.mol

Synonyms:1-(4’-METHYL)-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE

Suppliers and Price of 1-(4'-METHYL)-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(4'-METHYL)-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE 95.00%
5MG
$ 505.25

Total 4 raw suppliers

Chemical Property of 1-(4'-METHYL)-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE

Chemical Property:

PSA：12.03000
LogP:3.55890

Purity/Quality:

98%min ^*data from raw suppliers

1-(4'-METHYL)-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(4'-METHYL)-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE

There total 8 articles about 1-(4'-METHYL)-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 61305-03-1
1-(4'-methylphenyl)-3,4-dihydroisoquinoline

: 112891-31-3
1-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: With methanol; sodium tetrahydroborate; at 0 - 25 ℃; for 1h;
DOI:10.1039/d0ob02096f

Reference yield: 90.0%

: N-<(4-methylphenyl)methylene>benzeneethanamine

: 112891-31-3
1-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: With trifluorormethanesulfonic acid; at 120 ℃; for 3h;
DOI:10.1021/jo982019e

Reference yield: 69.0%

: 109-09-1
2-chloropyridine

: 358-23-6
trifluoromethylsulfonic anhydride

: 156-28-5
2-phenylethylamine hydrochloride

: 99-94-5
p-Toluic acid

: 112891-31-3
1-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: 2-phenylethylamine hydrochloride; p-Toluic acid; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; for 24h;

2-chloropyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at -78 ℃; for 51h; Reflux;

With sodium tetrahydroborate; In methanol; at 20 ℃; for 2h;
DOI:10.1021/jacs.7b00253