2-(2-amino-4-thiazolyl)-(Z)-2-[(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]thioacetic acid-S-benzothiazol-2-ylester

Base Information

• Chemical Name: 2-(2-amino-4-thiazolyl)-(Z)-2-[(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]thioacetic acid-S-benzothiazol-2-ylester
• CAS No.: 102253-85-0
• Molecular Formula: C₂₉H₂₄N₄O₄S₃
• Molecular Weight: 588.732
• Mol file: 102253-85-0.mol

Synonyms:2-(2-amino-4-thiazolyl)-(Z)-2-[(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]thioacetic acid-S-benzothiazol-2-ylester

Chemical Property of 2-(2-amino-4-thiazolyl)-(Z)-2-[(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]thioacetic acid-S-benzothiazol-2-ylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-amino-4-thiazolyl)-(Z)-2-[(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]thioacetic acid-S-benzothiazol-2-ylester

There total 1 articles about 2-(2-amino-4-thiazolyl)-(Z)-2-[(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]thioacetic acid-S-benzothiazol-2-ylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di(benzothiazol-2-yl)disulfide (120-78-5) + (Z)-2-Amino-α-[[2-(diphenylmethoxy)-1,1-dimethyl-2-oxoethoxy]-imino]-4-thiazoleacetic acid (80542-76-3,77497-47-3) → 2-(2-amino-4-thiazolyl)-(Z)-2-[(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]thioacetic acid-S-benzothiazol-2-ylester (102253-85-0)

Guidance literature:

With triphenylphosphine; In methanol; dichloromethane;

Reference yield:

N,O-bis-(trimethylsilyl)-acetamide (10416-59-8) + 2-(2-amino-4-thiazolyl)-(Z)-2-[(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]thioacetic acid-S-benzothiazol-2-ylester (102253-85-0) + 3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (24209-38-9) → (6R,7R)-7-[[2-(2-amino-4-thiazolyl)-(Z)-2-(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]acetamido]-3-[[(1-methyl-1H-5-tetrazolyl)thio]-methyl]-3-cephem-4-carboxylic acid (102267-65-2)

Guidance literature:

In dichloromethane;

Reference yield:

2-(2-amino-4-thiazolyl)-(Z)-2-[(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]thioacetic acid-S-benzothiazol-2-ylester (102253-85-0) + N,N-bis(trimethylsilyl)acetamide (10416-58-7) + 3-acetoxymethyl-7-aminoceph-3-em-4-carboxylic acid → (6R,7R)-3-acetoxymethyl-7-[[2-(2-amino-4-thiazolyl)-(Z)-2-(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]acetamido]-ceph-3-em-4-carboxylic acid (102253-87-2)

Guidance literature:

In dichloromethane;

upstream raw materials:

di(benzothiazol-2-yl)disulfide

(Z)-2-Amino-α-[[2-(diphenylmethoxy)-1,1-dimethyl-2-oxoethoxy]-imino]-4-thiazoleacetic acid

Downstream raw materials:

(6R,7R)-7-[[2-(2-amino-4-thiazolyl)-(Z)-2-(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]acetamido]-3-[[(1-methyl-1H-5-tetrazolyl)thio]-methyl]-3-cephem-4-carboxylic acid

(6R,7R)-3-acetoxymethyl-7-[[2-(2-amino-4-thiazolyl)-(Z)-2-(1-diphenylmethoxycarbonyl-1-methylethoxy)imino]acetamido]-ceph-3-em-4-carboxylic acid