(ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate

Base Information

Chemical Name:(ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate
CAS No.:866268-57-7
Molecular Formula:C₂₁H₂₇N₅O₄S
Molecular Weight:445.542
Hs Code.:

Synonyms:(ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate

Suppliers and Price of (ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate

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Technology Process of (ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate

There total 1 articles about (ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 866268-56-6
9-(2-bromoethyl)-2-(butyloxy)-8-(methyloxy)-9H-purin-6-amine

: 133806-71-0
3-mercaptophenylacetic acid methyl ester

: 866268-57-7
(ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

Reference yield: 42.0%

: 866268-57-7
(ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate

: 866268-65-7
methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]sulfonyl}phenyl)acetate

Guidance literature:: With Oxone; sodium carbonate; In water; acetone; at 20 ℃; for 0.5h;

Reference yield: 10.0%

: 67-56-1
methanol

: 866268-57-7
(ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate

: methyl (3-{[2-(6-amino2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)ethyl]-thio}phenyl)acetate

Guidance literature:: (ii)-Methyl (3-{[2-(6-amino-2-butoxy-8-methoxy-9H-purin-9-yl)ethyl]thio}-phenyl)acetate; With hydrogenchloride; water; In acetonitrile; for 17h; Heating;

methanol; With hydrogenchloride; In 1,4-dioxane; for 1h; Heating / reflux;

With water; sodium hydrogencarbonate; In ethyl acetate;