Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-2-methoxy-

Base Information

• Chemical Name: Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-2-methoxy-
• CAS No.: 112669-37-1
• Molecular Formula: C₁₂H₁₀Cl₂N₂O₂
• Molecular Weight: 285.13
• Mol file: 112669-37-1.mol

Synonyms:Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-2-methoxy-

Chemical Property of Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-2-methoxy-

Chemical Property:

• PSA: 44.12000
• LogP: 3.21780

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-2-methoxy-

There total 1 articles about Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-2-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1H-imidazole (288-32-4) + 1-(2,4-dichlorophenyl)-2,2-dimethoxyethanone (106836-88-8) → 2,4-Dichlor-α-(1-imidazolyl)-α-methoxyacetophenon (112669-37-1)

Guidance literature:

With Acetyl bromide; Yield given. Multistep reaction; 1.) room temperature, 1 h; 2.) THF/DMF, room temperature, 3 h;

Reference yield: 47.0%

methylmagnesium chloride (676-58-4) + 2,4-Dichlor-α-(1-imidazolyl)-α-methoxyacetophenon (112669-37-1) → (1R,2R/1S,2S)-2-(2,4-Dichlorphenyl)-1-(1-imidazolyl)-1-methoxy-2-propanol (106837-11-0)

Guidance literature:

In tetrahydrofuran; for 15h; Ambient temperature;

upstream raw materials:

1H-imidazole

1-(2,4-dichlorophenyl)-2,2-dimethoxyethanone

Downstream raw materials:

(1R,2R/1S,2S)-2-(2,4-Dichlorphenyl)-1-(1-imidazolyl)-1-methoxy-2-propanol

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