5,6-Dihydro-1H-[1,3]oxazino[5,4,3-ij]quinoline-3,7-dione

Base Information

Chemical Name:5,6-Dihydro-1H-[1,3]oxazino[5,4,3-ij]quinoline-3,7-dione
CAS No.:112646-14-7
Molecular Formula:C₁₁H₉NO₃
Molecular Weight:203.197
Hs Code.:
DSSTox Substance ID:DTXSID00562976
Mol file:112646-14-7.mol

Synonyms:112646-14-7;5,6-Dihydro-1H-[1,3]oxazino[5,4,3-ij]quinoline-3,7-dione;3-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene-2,10-dione;1H,3H,7H-Pyrido[3,2,1-ij][3,1]benzoxazine-3,7-dione, 5,6-dihydro- (9CI);CJCAYZAFFOFWCS-UHFFFAOYSA-N;SCHEMBL9827478;DTXSID00562976;3-oxa-1-azatricyclo[7.3.1.0,]trideca-5,7,9(13)-triene-2,10-dione;5,6-Dihydro-1H,3H,7H-[1,3]oxazino[5,4,3-ij]quinoline-3,7-dione;6,7-dihydro-3,7-dioxo-1H,3H,5H-pyrido [3,2,1-ij][3,1]benzoxazine;6,7-Dihydro-3,7-dioxo-1H,3H,5H-pyrido[3,2,1-ij][3,1]benzoxazine;1H,3H,7H-Pyrido[3,2,1-ij][3,1]benzoxazine-3,7-dione,5,6-dihydro-(9ci);3-oxa-1-azatricyclo[7.3.1.0,(1)(3)]trideca-5,7,9(13)-triene-2,10-dione

Suppliers and Price of 5,6-Dihydro-1H-[1,3]oxazino[5,4,3-ij]quinoline-3,7-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5,6-Dihydro-1H-[1,3]oxazino[5,4,3-ij]quinoline-3,7-dione

Chemical Property:

PSA：46.61000
LogP:1.79460
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:203.058243149
Heavy Atom Count:15
Complexity:315

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2C3=C(COC2=O)C=CC=C3C1=O

Technology Process of 5,6-Dihydro-1H-[1,3]oxazino[5,4,3-ij]quinoline-3,7-dione

There total 5 articles about 5,6-Dihydro-1H-[1,3]oxazino[5,4,3-ij]quinoline-3,7-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 112646-13-6
3-(4H-1,2-Dihydro-2-oxo-3,1-benzoxazin-1-yl)propionic Acid

: 112646-14-7
1H,3H,5H,6H,7H-3,7-Dioxopyrido<3,2,1-ij><3,1>benzoxazine

Guidance literature:: With PPA; at 120 ℃; for 1h;
DOI:10.1248/cpb.38.1575

Reference yield:

: 112646-13-6
3-(4H-1,2-Dihydro-2-oxo-3,1-benzoxazin-1-yl)propionic Acid

PPA: PPA

: 112646-14-7
1H,3H,5H,6H,7H-3,7-Dioxopyrido<3,2,1-ij><3,1>benzoxazine

Guidance literature:: With phosphorus pentaoxide; phosphoric acid; In water;

Reference yield:

: 5344-90-1
2-Aminobenzyl alcohol

: 112646-14-7
1H,3H,5H,6H,7H-3,7-Dioxopyrido<3,2,1-ij><3,1>benzoxazine

Guidance literature:: Multi-step reaction with 4 steps

1: 74 percent / Et₃N / tetrahydrofuran / 2 h / Ambient temperature

2: 90 percent / K₂CO₃ / dimethylformamide / 5 h / 50 °C

3: 92 percent / Na₂CO₃ / methanol / 8 h / Heating

4: 60 percent / polyphosphoric acid / 1 h / 120 °C

With PPA; sodium carbonate; potassium carbonate; triethylamine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1248/cpb.38.1575